Higher nucleoporin-Importinβ affinity at the nuclear basket increases nucleocytoplasmic import.
Several in vitro studies have shown the presence of an affinity gradient in nuclear pore complex proteins for the import receptor Importinβ, at least partially contributing to nucleocytoplasmic transport, while others have historically argued against the presence of such a gradient. Nonetheless, the...
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Main Authors: | , |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/cb92e89e32a1406a8787f38e05f59d1f |
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