Analysis of polygenic risk score usage and performance in diverse human populations

Predominant participation of European-ancestry individuals in genetic studies has hindered the better understanding of genetic risk in non-European ancestry individuals. Here, Duncan et al. quantify polygenic risk score use and performance in worldwide populations.

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Detalles Bibliográficos
Autores principales: L. Duncan, H. Shen, B. Gelaye, J. Meijsen, K. Ressler, M. Feldman, R. Peterson, B. Domingue
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cb93a6b3791441d4a1f333febc9cc943
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Sumario:Predominant participation of European-ancestry individuals in genetic studies has hindered the better understanding of genetic risk in non-European ancestry individuals. Here, Duncan et al. quantify polygenic risk score use and performance in worldwide populations.