Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series

The year 2020 saw the rise of an influenza-like illness from SARS-nCoV2 (Severe Acute Respiratory Illness by novel Coronavirus 2), which causes myriad of symptoms in patients, ranging from mild upper respiratory symptoms to severe ARDS (Acute Respiratory Distress Syndrome). It is, however, known to...

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Autores principales: Mudit Varshney, Amandeep Jaswal, Sahil Diwan, Santvana Kohli, Ruqaiya Bano, Harish C. Sachdeva, G. Usha
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Publicado: Tehran University of Medical Sciences 2021
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spelling oai:doaj.org-article:cb9999621ce84dfaa2e4dd43b4b8f5222021-11-20T04:39:28ZIs COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series10.18502/aacc.v7i4.76372423-5849https://doaj.org/article/cb9999621ce84dfaa2e4dd43b4b8f5222021-10-01T00:00:00Zhttps://aacc.tums.ac.ir/index.php/aacc/article/view/375https://doaj.org/toc/2423-5849 The year 2020 saw the rise of an influenza-like illness from SARS-nCoV2 (Severe Acute Respiratory Illness by novel Coronavirus 2), which causes myriad of symptoms in patients, ranging from mild upper respiratory symptoms to severe ARDS (Acute Respiratory Distress Syndrome). It is, however, known to cause high morbidity and mortality in patients with underlying comorbidities like diabetes, hypertension, kidney disease, obesity and malignancies. Amongst these, the subset with haematological malignancies has an especially poor prognosis possibly as a result of immune suppression, due to underlying bone marrow depression as well as effects of chemotherapeutic agents. These patients need frequent visits and admissions to the hospital for treatment, thus exposing them to the risk of acquiring the infection. Also, a high index of suspicion, with low threshold for testing is needed in view of possible atypical presentation and symptoms. These patients may also warrant an early ICU admission, as they tend to develop severe disease with ARDS more frequently, with an overall poor prognosis and high mortality rate. We hereby present a series of six patients with underlying haematological malignancies who were admitted in our ICU with a serious COVID-19 illness and a grave outcome. Mudit VarshneyAmandeep JaswalSahil DiwanSantvana KohliRuqaiya BanoHarish C. SachdevaG. UshaTehran University of Medical SciencesarticleChemotherapyCOVID-19SARS-nCoV 2MalignancyHaematological MalignancyMortalityAnesthesiologyRD78.3-87.3Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENArchives of Anesthesia and Critical Care, Vol 7, Iss 4 (2021)
institution DOAJ
collection DOAJ
language EN
topic Chemotherapy
COVID-19
SARS-nCoV 2
Malignancy
Haematological Malignancy
Mortality
Anesthesiology
RD78.3-87.3
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle Chemotherapy
COVID-19
SARS-nCoV 2
Malignancy
Haematological Malignancy
Mortality
Anesthesiology
RD78.3-87.3
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Mudit Varshney
Amandeep Jaswal
Sahil Diwan
Santvana Kohli
Ruqaiya Bano
Harish C. Sachdeva
G. Usha
Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
description The year 2020 saw the rise of an influenza-like illness from SARS-nCoV2 (Severe Acute Respiratory Illness by novel Coronavirus 2), which causes myriad of symptoms in patients, ranging from mild upper respiratory symptoms to severe ARDS (Acute Respiratory Distress Syndrome). It is, however, known to cause high morbidity and mortality in patients with underlying comorbidities like diabetes, hypertension, kidney disease, obesity and malignancies. Amongst these, the subset with haematological malignancies has an especially poor prognosis possibly as a result of immune suppression, due to underlying bone marrow depression as well as effects of chemotherapeutic agents. These patients need frequent visits and admissions to the hospital for treatment, thus exposing them to the risk of acquiring the infection. Also, a high index of suspicion, with low threshold for testing is needed in view of possible atypical presentation and symptoms. These patients may also warrant an early ICU admission, as they tend to develop severe disease with ARDS more frequently, with an overall poor prognosis and high mortality rate. We hereby present a series of six patients with underlying haematological malignancies who were admitted in our ICU with a serious COVID-19 illness and a grave outcome.
format article
author Mudit Varshney
Amandeep Jaswal
Sahil Diwan
Santvana Kohli
Ruqaiya Bano
Harish C. Sachdeva
G. Usha
author_facet Mudit Varshney
Amandeep Jaswal
Sahil Diwan
Santvana Kohli
Ruqaiya Bano
Harish C. Sachdeva
G. Usha
author_sort Mudit Varshney
title Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
title_short Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
title_full Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
title_fullStr Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
title_full_unstemmed Is COVID-19 Infection a Death Sentence in Patients Living with Haematological Malignancies? A Case Series
title_sort is covid-19 infection a death sentence in patients living with haematological malignancies? a case series
publisher Tehran University of Medical Sciences
publishDate 2021
url https://doaj.org/article/cb9999621ce84dfaa2e4dd43b4b8f522
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