A Gaussia luciferase cell-based system to assess the infection of cell culture- and serum-derived hepatitis C virus.

Robust replication of hepatitis C virus (HCV) in cell culture occurs only with the JFH-1 (genotype 2a) recombinant genome. The aim of this study was to develop a system for HCV infection quantification analysis and apply it for the selection of patient sera that may contain cell culture infectious v...

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Autores principales: George Koutsoudakis, Sofía Pérez-del-Pulgar, Patricia González, Gonzalo Crespo, Miquel Navasa, Xavier Forns
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/cb99fe127d4544c3bcc0ffcebba08a8d
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