An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link.
Two factors contribute to Burkitt lymphoma (BL) pathogenesis, a chromosomal translocation leading to c-myc oncogene deregulation and infection with Epstein-Barr virus (EBV). Although the virus has B cell growth-transforming ability, this may not relate to its role in BL since many of the transformin...
Enregistré dans:
Auteurs principaux: | Gemma L Kelly, Heather M Long, Julianna Stylianou, Wendy A Thomas, Alison Leese, Andrew I Bell, Georg W Bornkamm, Josef Mautner, Alan B Rickinson, Martin Rowe |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/cba3c46e566143f5bbe3462e7f791529 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines
par: Hector Hernandez-Vargas, et autres
Publié: (2017) -
Epstein-Barr virus-induced gene 3 (EBI3): a novel diagnosis marker in Burkitt lymphoma and diffuse large B-cell lymphoma.
par: Julie Gonin, et autres
Publié: (2011) -
Epstein–Barr virus particles induce centrosome amplification and chromosomal instability
par: Anatoliy Shumilov, et autres
Publié: (2017) -
Atomic structure of the Epstein-Barr virus portal
par: Cristina Machón, et autres
Publié: (2019) -
Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.
par: Emily Heath, et autres
Publié: (2012)