An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link.

Two factors contribute to Burkitt lymphoma (BL) pathogenesis, a chromosomal translocation leading to c-myc oncogene deregulation and infection with Epstein-Barr virus (EBV). Although the virus has B cell growth-transforming ability, this may not relate to its role in BL since many of the transformin...

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Bibliographic Details
Main Authors: Gemma L Kelly, Heather M Long, Julianna Stylianou, Wendy A Thomas, Alison Leese, Andrew I Bell, Georg W Bornkamm, Josef Mautner, Alan B Rickinson, Martin Rowe
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
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Online Access:https://doaj.org/article/cba3c46e566143f5bbe3462e7f791529
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