Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.

Successful scale-up of PrEP for HIV prevention in African adolescent girls and young women (AGYW) requires integration of PrEP into young women's everyday lives. We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and r...

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Autores principales:	Elzette Rousseau, Ariana W K Katz, Shannon O'Rourke, Linda-Gail Bekker, Sinead Delany-Moretlwe, Elizabeth Bukusi, Danielle Travill, Victor Omollo, Jennifer F Morton, Gabrielle O'Malley, Jessica E Haberer, Renee Heffron, Rachel Johnson, Connie Celum, Jared M Baeten, Ariane van der Straten
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cbadd27d13d9478da1837897139170a9
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spelling	oai:doaj.org-article:cbadd27d13d9478da1837897139170a92021-12-02T20:19:11ZAdolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.1932-620310.1371/journal.pone.0258542https://doaj.org/article/cbadd27d13d9478da1837897139170a92021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0258542https://doaj.org/toc/1932-6203Successful scale-up of PrEP for HIV prevention in African adolescent girls and young women (AGYW) requires integration of PrEP into young women's everyday lives. We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and relational enablers and disablers were explored at key moments during their PrEP-user journey from awareness, initiation and early use through persistence, including PrEP pauses, restarts, and discontinuation. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community. Daily pill-taking was challenging for AGYW due to individual, relational and structural factors and PrEP interruptions (intended or unintended) were described as part of AGYW's PrEP-user journey. Disclosure, social support, adolescent-friendly health counseling, and convenient access to PrEP were reported as key enablers for PrEP persistence.Elzette RousseauAriana W K KatzShannon O'RourkeLinda-Gail BekkerSinead Delany-MoretlweElizabeth BukusiDanielle TravillVictor OmolloJennifer F MortonGabrielle O'MalleyJessica E HabererRenee HeffronRachel JohnsonConnie CelumJared M BaetenAriane van der StratenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0258542 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Elzette Rousseau Ariana W K Katz Shannon O'Rourke Linda-Gail Bekker Sinead Delany-Moretlwe Elizabeth Bukusi Danielle Travill Victor Omollo Jennifer F Morton Gabrielle O'Malley Jessica E Haberer Renee Heffron Rachel Johnson Connie Celum Jared M Baeten Ariane van der Straten Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
description	Successful scale-up of PrEP for HIV prevention in African adolescent girls and young women (AGYW) requires integration of PrEP into young women's everyday lives. We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and relational enablers and disablers were explored at key moments during their PrEP-user journey from awareness, initiation and early use through persistence, including PrEP pauses, restarts, and discontinuation. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community. Daily pill-taking was challenging for AGYW due to individual, relational and structural factors and PrEP interruptions (intended or unintended) were described as part of AGYW's PrEP-user journey. Disclosure, social support, adolescent-friendly health counseling, and convenient access to PrEP were reported as key enablers for PrEP persistence.
format	article
author	Elzette Rousseau Ariana W K Katz Shannon O'Rourke Linda-Gail Bekker Sinead Delany-Moretlwe Elizabeth Bukusi Danielle Travill Victor Omollo Jennifer F Morton Gabrielle O'Malley Jessica E Haberer Renee Heffron Rachel Johnson Connie Celum Jared M Baeten Ariane van der Straten
author_facet	Elzette Rousseau Ariana W K Katz Shannon O'Rourke Linda-Gail Bekker Sinead Delany-Moretlwe Elizabeth Bukusi Danielle Travill Victor Omollo Jennifer F Morton Gabrielle O'Malley Jessica E Haberer Renee Heffron Rachel Johnson Connie Celum Jared M Baeten Ariane van der Straten
author_sort	Elzette Rousseau
title	Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
title_short	Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
title_full	Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
title_fullStr	Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
title_full_unstemmed	Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.
title_sort	adolescent girls and young women's prep-user journey during an implementation science study in south africa and kenya.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/cbadd27d13d9478da1837897139170a9
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Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya.

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