Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination.

Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination.

Next-generation sequencing (NGS) is a valuable tool for the detection and quantification of HIV-1 variants in vivo. However, these technologies require detailed characterization and control of artificially induced errors to be applicable for accurate haplotype reconstruction. To investigate the occu...

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Autores principales: Francesca Di Giallonardo, Osvaldo Zagordi, Yannick Duport, Christine Leemann, Beda Joos, Marzanna Künzli-Gontarczyk, Rémy Bruggmann, Niko Beerenwinkel, Huldrych F Günthard, Karin J Metzner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cbaeb1fe1e194334a7b02f6c778379f5
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