A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

Respiratory complex I plays a central role in cellular energy metabolism coupling NADH oxidation to proton translocation. Here, the authors report the structure of the electron input part of Aquifex aeolicus complex I at up to 1.8 Å resolution with bound substrates in the reduced and oxidized states...

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Autores principales: Marius Schulte, Klaudia Frick, Emmanuel Gnandt, Sascha Jurkovic, Sabrina Burschel, Ramona Labatzke, Karoline Aierstock, Dennis Fiegen, Daniel Wohlwend, Stefan Gerhardt, Oliver Einsle, Thorsten Friedrich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cbb18c1443da4b2783df8204ef6ed1bb
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Sumario:Respiratory complex I plays a central role in cellular energy metabolism coupling NADH oxidation to proton translocation. Here, the authors report the structure of the electron input part of Aquifex aeolicus complex I at up to 1.8 Å resolution with bound substrates in the reduced and oxidized states.