Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement

Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement

Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled ba...

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Auteurs principaux: Y. Z. Shi, S. Xiong, Y. Zhang, L. K. Chin, Y. –Y. Chen, J. B. Zhang, T. H. Zhang, W. Ser, A. Larrson, S. H. Lim, J. H. Wu, T. N. Chen, Z. C. Yang, Y. L. Hao, B. Liedberg, P. H. Yap, K. Wang, D. P. Tsai, C.-W. Qiu, A. Q. Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Science
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Accès en ligne:https://doaj.org/article/cbc16d1a0bae4d40ab46391c53d9bd83
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Résumé:Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled bacteria hopping.

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