Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement

Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled ba...

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Autores principales: Y. Z. Shi, S. Xiong, Y. Zhang, L. K. Chin, Y. –Y. Chen, J. B. Zhang, T. H. Zhang, W. Ser, A. Larrson, S. H. Lim, J. H. Wu, T. N. Chen, Z. C. Yang, Y. L. Hao, B. Liedberg, P. H. Yap, K. Wang, D. P. Tsai, C.-W. Qiu, A. Q. Liu
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/cbc16d1a0bae4d40ab46391c53d9bd83
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spelling oai:doaj.org-article:cbc16d1a0bae4d40ab46391c53d9bd832021-12-02T17:31:13ZSculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement10.1038/s41467-018-03156-52041-1723https://doaj.org/article/cbc16d1a0bae4d40ab46391c53d9bd832018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03156-5https://doaj.org/toc/2041-1723Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled bacteria hopping.Y. Z. ShiS. XiongY. ZhangL. K. ChinY. –Y. ChenJ. B. ZhangT. H. ZhangW. SerA. LarrsonS. H. LimJ. H. WuT. N. ChenZ. C. YangY. L. HaoB. LiedbergP. H. YapK. WangD. P. TsaiC.-W. QiuA. Q. LiuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Y. Z. Shi
S. Xiong
Y. Zhang
L. K. Chin
Y. –Y. Chen
J. B. Zhang
T. H. Zhang
W. Ser
A. Larrson
S. H. Lim
J. H. Wu
T. N. Chen
Z. C. Yang
Y. L. Hao
B. Liedberg
P. H. Yap
K. Wang
D. P. Tsai
C.-W. Qiu
A. Q. Liu
Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
description Optical trapping is a versatile tool for biomedical applications. Here, the authors use an optofluidic lattice to achieve controllable multi-particle hopping and demonstrate single-bacteria-level screening and measurement of binding efficiency of biological binding agents through particle-enabled bacteria hopping.
format article
author Y. Z. Shi
S. Xiong
Y. Zhang
L. K. Chin
Y. –Y. Chen
J. B. Zhang
T. H. Zhang
W. Ser
A. Larrson
S. H. Lim
J. H. Wu
T. N. Chen
Z. C. Yang
Y. L. Hao
B. Liedberg
P. H. Yap
K. Wang
D. P. Tsai
C.-W. Qiu
A. Q. Liu
author_facet Y. Z. Shi
S. Xiong
Y. Zhang
L. K. Chin
Y. –Y. Chen
J. B. Zhang
T. H. Zhang
W. Ser
A. Larrson
S. H. Lim
J. H. Wu
T. N. Chen
Z. C. Yang
Y. L. Hao
B. Liedberg
P. H. Yap
K. Wang
D. P. Tsai
C.-W. Qiu
A. Q. Liu
author_sort Y. Z. Shi
title Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
title_short Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
title_full Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
title_fullStr Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
title_full_unstemmed Sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
title_sort sculpting nanoparticle dynamics for single-bacteria-level screening and direct binding-efficiency measurement
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/cbc16d1a0bae4d40ab46391c53d9bd83
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