A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection
The response to respiratory virus exposure can currently not be predicted by pre- or early post-exposure molecular signatures. Here, the authors conduct a community-based analysis of blood gene expression from healthy individuals exposed to respiratory viruses and provide predictive models and biolo...
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Nature Portfolio
2018
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oai:doaj.org-article:cbc4730ec0cb4a8bba4f75028fefde372021-12-02T14:39:24ZA crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection10.1038/s41467-018-06735-82041-1723https://doaj.org/article/cbc4730ec0cb4a8bba4f75028fefde372018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06735-8https://doaj.org/toc/2041-1723The response to respiratory virus exposure can currently not be predicted by pre- or early post-exposure molecular signatures. Here, the authors conduct a community-based analysis of blood gene expression from healthy individuals exposed to respiratory viruses and provide predictive models and biological insight into the physiological response.Slim FouratiAarthi TallaMehrad MahmoudianJoshua G. BurkhartRiku KlénRicardo HenaoThomas YuZafer AydınKa Yee YeungMehmet Eren AhsenReem AlmugbelSamad JahandidehXiao LiangTorbjörn E. M. NordlingMotoki ShigaAna StanescuRobert VogelThe Respiratory Viral DREAM Challenge ConsortiumGaurav PandeyChristopher ChiuMicah T. McClainChristopher W. WoodsGeoffrey S. GinsburgLaura L. EloEphraim L. TsalikLara M. MangraviteSolveig K. SiebertsNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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DOAJ |
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| topic |
Science Q |
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Science Q Slim Fourati Aarthi Talla Mehrad Mahmoudian Joshua G. Burkhart Riku Klén Ricardo Henao Thomas Yu Zafer Aydın Ka Yee Yeung Mehmet Eren Ahsen Reem Almugbel Samad Jahandideh Xiao Liang Torbjörn E. M. Nordling Motoki Shiga Ana Stanescu Robert Vogel The Respiratory Viral DREAM Challenge Consortium Gaurav Pandey Christopher Chiu Micah T. McClain Christopher W. Woods Geoffrey S. Ginsburg Laura L. Elo Ephraim L. Tsalik Lara M. Mangravite Solveig K. Sieberts A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| description |
The response to respiratory virus exposure can currently not be predicted by pre- or early post-exposure molecular signatures. Here, the authors conduct a community-based analysis of blood gene expression from healthy individuals exposed to respiratory viruses and provide predictive models and biological insight into the physiological response. |
| format |
article |
| author |
Slim Fourati Aarthi Talla Mehrad Mahmoudian Joshua G. Burkhart Riku Klén Ricardo Henao Thomas Yu Zafer Aydın Ka Yee Yeung Mehmet Eren Ahsen Reem Almugbel Samad Jahandideh Xiao Liang Torbjörn E. M. Nordling Motoki Shiga Ana Stanescu Robert Vogel The Respiratory Viral DREAM Challenge Consortium Gaurav Pandey Christopher Chiu Micah T. McClain Christopher W. Woods Geoffrey S. Ginsburg Laura L. Elo Ephraim L. Tsalik Lara M. Mangravite Solveig K. Sieberts |
| author_facet |
Slim Fourati Aarthi Talla Mehrad Mahmoudian Joshua G. Burkhart Riku Klén Ricardo Henao Thomas Yu Zafer Aydın Ka Yee Yeung Mehmet Eren Ahsen Reem Almugbel Samad Jahandideh Xiao Liang Torbjörn E. M. Nordling Motoki Shiga Ana Stanescu Robert Vogel The Respiratory Viral DREAM Challenge Consortium Gaurav Pandey Christopher Chiu Micah T. McClain Christopher W. Woods Geoffrey S. Ginsburg Laura L. Elo Ephraim L. Tsalik Lara M. Mangravite Solveig K. Sieberts |
| author_sort |
Slim Fourati |
| title |
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| title_short |
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| title_full |
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| title_fullStr |
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| title_full_unstemmed |
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| title_sort |
crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/cbc4730ec0cb4a8bba4f75028fefde37 |
| work_keys_str_mv |
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