Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

Sensitive diagnostic tools for bacterial infections of wounds and surgical sites are necessary to enable early detection and determine optimal means of treatment. Here, the authors develop a fluorescent and optoacoustic probe based on a maltotriose scaffold, which is selectively taken up by gram-pos...

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Bibliographic Details
Main Authors: Aimen Zlitni, Gayatri Gowrishankar, Idan Steinberg, Tom Haywood, Sanjiv Sam Gambhir
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/cbc5491413a449c4b79b71078cee23b4
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Summary:Sensitive diagnostic tools for bacterial infections of wounds and surgical sites are necessary to enable early detection and determine optimal means of treatment. Here, the authors develop a fluorescent and optoacoustic probe based on a maltotriose scaffold, which is selectively taken up by gram-positive and gram-negative bacteria.