Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD
The role of exosome-mediated mitophagy in the crosstalk between hepatocytes (HCs) and hepatic stellate cells (HSCs) in metabolic-associated fatty liver disease (MAFLD) remains unknown. Serum exosomal miR-27a levels were markedly increased and positively correlated with liver fibrosis in MAFLD patien...
Guardado en:
Autores principales: | Xin Luo, Zi-Xin Xu, Jun-Cheng Wu, Sheng-Zheng Luo, Ming-Yi Xu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/cbd16e2f695b429f9a8bc38683761f6d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
MicroRNA-27b Expression in Rats Submitted to Physical Exercise and Experimental Cerebral Ischemia
por: De-Russi,Brenno Marco, et al.
Publicado: (2021) -
MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy
por: Dou Shi-Ying, et al.
Publicado: (2021) -
microRNA-27a-3p but Not -5p Is a Crucial Mediator of Human Adipogenesis
por: Hang Wu, et al.
Publicado: (2021) -
Serum Micro-RNA-122 Level as a Simple Noninvasive Marker of MAFLD Severity
por: Hegazy MA, et al.
Publicado: (2021) -
Upregulation of MiR-196a promotes cell proliferation by downregulating p27kip1 in laryngeal cancer
por: Cheng,Jin, et al.
Publicado: (2016)