Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD

The role of exosome-mediated mitophagy in the crosstalk between hepatocytes (HCs) and hepatic stellate cells (HSCs) in metabolic-associated fatty liver disease (MAFLD) remains unknown. Serum exosomal miR-27a levels were markedly increased and positively correlated with liver fibrosis in MAFLD patien...

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Détails bibliographiques
Auteurs principaux: Xin Luo, Zi-Xin Xu, Jun-Cheng Wu, Sheng-Zheng Luo, Ming-Yi Xu
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/cbd16e2f695b429f9a8bc38683761f6d
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