Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex

Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.

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Bibliographic Details
Main Authors: XiaoTing Zheng, Kirstie J. Salinas, Dario X. Figueroa Velez, Taylor Nakayama, Xiaoxiao Lin, Dhruba Banerjee, Xiangmin Xu, Sunil P. Gandhi
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df48
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Summary:Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.