Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex

Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.

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Autores principales: XiaoTing Zheng, Kirstie J. Salinas, Dario X. Figueroa Velez, Taylor Nakayama, Xiaoxiao Lin, Dhruba Banerjee, Xiangmin Xu, Sunil P. Gandhi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df48
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spelling oai:doaj.org-article:cbd298a18fce46f5a8cd7b6b60a3df482021-12-02T14:11:09ZHost interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex10.1038/s41467-021-21097-42041-1723https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df482021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21097-4https://doaj.org/toc/2041-1723Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.XiaoTing ZhengKirstie J. SalinasDario X. Figueroa VelezTaylor NakayamaXiaoxiao LinDhruba BanerjeeXiangmin XuSunil P. GandhiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
XiaoTing Zheng
Kirstie J. Salinas
Dario X. Figueroa Velez
Taylor Nakayama
Xiaoxiao Lin
Dhruba Banerjee
Xiangmin Xu
Sunil P. Gandhi
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
description Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.
format article
author XiaoTing Zheng
Kirstie J. Salinas
Dario X. Figueroa Velez
Taylor Nakayama
Xiaoxiao Lin
Dhruba Banerjee
Xiangmin Xu
Sunil P. Gandhi
author_facet XiaoTing Zheng
Kirstie J. Salinas
Dario X. Figueroa Velez
Taylor Nakayama
Xiaoxiao Lin
Dhruba Banerjee
Xiangmin Xu
Sunil P. Gandhi
author_sort XiaoTing Zheng
title Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
title_short Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
title_full Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
title_fullStr Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
title_full_unstemmed Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
title_sort host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df48
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