Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex
Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.
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Nature Portfolio
2021
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oai:doaj.org-article:cbd298a18fce46f5a8cd7b6b60a3df482021-12-02T14:11:09ZHost interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex10.1038/s41467-021-21097-42041-1723https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df482021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21097-4https://doaj.org/toc/2041-1723Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons.XiaoTing ZhengKirstie J. SalinasDario X. Figueroa VelezTaylor NakayamaXiaoxiao LinDhruba BanerjeeXiangmin XuSunil P. GandhiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q XiaoTing Zheng Kirstie J. Salinas Dario X. Figueroa Velez Taylor Nakayama Xiaoxiao Lin Dhruba Banerjee Xiangmin Xu Sunil P. Gandhi Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
description |
Transplantation of embryonic interneurons can restore juvenile plasticity to the adult host visual cortex. Here, the authors show that transplanted embryonic interneurons reactivate cortical plasticity via Neuregulin/ErbB4 signaling in host parvalbumin interneurons. |
format |
article |
author |
XiaoTing Zheng Kirstie J. Salinas Dario X. Figueroa Velez Taylor Nakayama Xiaoxiao Lin Dhruba Banerjee Xiangmin Xu Sunil P. Gandhi |
author_facet |
XiaoTing Zheng Kirstie J. Salinas Dario X. Figueroa Velez Taylor Nakayama Xiaoxiao Lin Dhruba Banerjee Xiangmin Xu Sunil P. Gandhi |
author_sort |
XiaoTing Zheng |
title |
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
title_short |
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
title_full |
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
title_fullStr |
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
title_full_unstemmed |
Host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
title_sort |
host interneurons mediate plasticity reactivated by embryonic inhibitory cell transplantation in mouse visual cortex |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/cbd298a18fce46f5a8cd7b6b60a3df48 |
work_keys_str_mv |
AT xiaotingzheng hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT kirstiejsalinas hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT darioxfigueroavelez hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT taylornakayama hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT xiaoxiaolin hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT dhrubabanerjee hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT xiangminxu hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex AT sunilpgandhi hostinterneuronsmediateplasticityreactivatedbyembryonicinhibitorycelltransplantationinmousevisualcortex |
_version_ |
1718391869580247040 |