Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.

Conventional reverse genetic approaches for study of Plasmodium malaria parasite gene function are limited, or not applicable. Hence, new inducible systems are needed. Here we describe a method to control P. falciparum gene expression in which target genes bearing a glmS ribozyme in the 3' untr...

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Autores principales: Parichat Prommana, Chairat Uthaipibull, Chayaphat Wongsombat, Sumalee Kamchonwongpaisan, Yongyuth Yuthavong, Ellen Knuepfer, Anthony A Holder, Philip J Shaw
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cbdb79dbc4e3405a975346b77b49e550
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