Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
The severity of ulcerative colitis, and response to treatment, is highly variable. Here, the authors examine rectal gene expression signatures and faecal microbiomes of children and adults with the disease and provide new insights in to pathogenesis.
Enregistré dans:
Auteurs principaux: | Yael Haberman, Rebekah Karns, Phillip J. Dexheimer, Melanie Schirmer, Judith Somekh, Ingrid Jurickova, Tzipi Braun, Elizabeth Novak, Laura Bauman, Margaret H. Collins, Angela Mo, Michael J. Rosen, Erin Bonkowski, Nathan Gotman, Alison Marquis, Mason Nistel, Paul A. Rufo, Susan S. Baker, Cary G. Sauer, James Markowitz, Marian D. Pfefferkorn, Joel R. Rosh, Brendan M. Boyle, David R. Mack, Robert N. Baldassano, Sapana Shah, Neal S. Leleiko, Melvin B. Heyman, Anne M. Grifiths, Ashish S. Patel, Joshua D. Noe, Bruce J. Aronow, Subra Kugathasan, Thomas D. Walters, Greg Gibson, Sonia Davis Thomas, Kevin Mollen, Shai Shen-Orr, Curtis Huttenhower, Ramnik J. Xavier, Jeffrey S. Hyams, Lee A. Denson |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/cbe3d637f8854aa08026fcc4f3d0a9e7 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
par: Sanam Soomro, et autres
Publié: (2021) -
Low-frequency theta oscillations in the human hippocampus during real-world and virtual navigation
par: Véronique D. Bohbot, et autres
Publié: (2017) -
SARS-CoV-2 does not have a strong effect on the nasopharyngeal microbial composition
par: Tzipi Braun, et autres
Publié: (2021) -
Patrick Le Galès (dir.), Gouverner la métropole parisienne. État, conflits, institutions, réseaux
par: Philippe Subra
Publié: (2021) -
Dramaturgias brechtianas recientes a partir de «Fuenteovejuna»
par: Sergio Adillo Rufo
Publié: (2018)