Rising midlife obesity will worsen future prevalence of dementia.

<h4>Background</h4>Midlife body weight status has been found to affect late life dementia outcomes. A cohort projections model was developed to assess the impact of midlife body mass index (BMI) profile on dementia in older Australians.<h4>Methods</h4>A baseline projection us...

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Autores principales:	Binod Nepal, Laurie J Brown, Kaarin J Anstey
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cbe93c06cadd4374a7b782f8348174aa
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spelling	oai:doaj.org-article:cbe93c06cadd4374a7b782f8348174aa2021-11-25T06:01:56ZRising midlife obesity will worsen future prevalence of dementia.1932-620310.1371/journal.pone.0099305https://doaj.org/article/cbe93c06cadd4374a7b782f8348174aa2014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25184830/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Midlife body weight status has been found to affect late life dementia outcomes. A cohort projections model was developed to assess the impact of midlife body mass index (BMI) profile on dementia in older Australians.<h4>Methods</h4>A baseline projection using age-sex specific dementia prevalence rates was constructed and the results of scenarios that took account of midlife BMI were compared with those from population ageing only.<h4>Results</h4>This modelling predicts that if the rising trend in midlife obesity and declining trend in midlife normal weight in Australia are to be taken into account in projecting future numbers of Australians with dementia then the number of people aged 65 or more years with dementia, by 2050, would be 14% higher than that expected from demographic ageing only. If midlife obesity prevalence was decreased to 20% and normal weight increased to 40% over the period of 2015-2025, then dementia cases among persons aged 65-69 years would be lower by about 10% in 2050 compared with the "doing nothing to stop current trends in obesity" projection.<h4>Conclusion</h4>The rising tide of obesity in Australian adults will increase the dementia epidemic expected in future years.Binod NepalLaurie J BrownKaarin J AnsteyPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 9, p e99305 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Binod Nepal Laurie J Brown Kaarin J Anstey Rising midlife obesity will worsen future prevalence of dementia.
description	<h4>Background</h4>Midlife body weight status has been found to affect late life dementia outcomes. A cohort projections model was developed to assess the impact of midlife body mass index (BMI) profile on dementia in older Australians.<h4>Methods</h4>A baseline projection using age-sex specific dementia prevalence rates was constructed and the results of scenarios that took account of midlife BMI were compared with those from population ageing only.<h4>Results</h4>This modelling predicts that if the rising trend in midlife obesity and declining trend in midlife normal weight in Australia are to be taken into account in projecting future numbers of Australians with dementia then the number of people aged 65 or more years with dementia, by 2050, would be 14% higher than that expected from demographic ageing only. If midlife obesity prevalence was decreased to 20% and normal weight increased to 40% over the period of 2015-2025, then dementia cases among persons aged 65-69 years would be lower by about 10% in 2050 compared with the "doing nothing to stop current trends in obesity" projection.<h4>Conclusion</h4>The rising tide of obesity in Australian adults will increase the dementia epidemic expected in future years.
format	article
author	Binod Nepal Laurie J Brown Kaarin J Anstey
author_facet	Binod Nepal Laurie J Brown Kaarin J Anstey
author_sort	Binod Nepal
title	Rising midlife obesity will worsen future prevalence of dementia.
title_short	Rising midlife obesity will worsen future prevalence of dementia.
title_full	Rising midlife obesity will worsen future prevalence of dementia.
title_fullStr	Rising midlife obesity will worsen future prevalence of dementia.
title_full_unstemmed	Rising midlife obesity will worsen future prevalence of dementia.
title_sort	rising midlife obesity will worsen future prevalence of dementia.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/cbe93c06cadd4374a7b782f8348174aa
work_keys_str_mv	AT binodnepal risingmidlifeobesitywillworsenfutureprevalenceofdementia AT lauriejbrown risingmidlifeobesitywillworsenfutureprevalenceofdementia AT kaarinjanstey risingmidlifeobesitywillworsenfutureprevalenceofdementia
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Rising midlife obesity will worsen future prevalence of dementia.

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