Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe

Abstract Hypoxia is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply. In hypoxic solid tumors, an increased expression of nitroreductase (NTR) is detected, therefore, the development of NTR-targeted fluorescent probes to selectively...

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Auteurs principaux: Dan Yang, Hang Yu Tian, Tie Nan Zang, Ming Li, Ying Zhou, Jun Feng Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/cbf1821b71684008af08a97dbb458eea
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