Hypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe
Abstract Hypoxia is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply. In hypoxic solid tumors, an increased expression of nitroreductase (NTR) is detected, therefore, the development of NTR-targeted fluorescent probes to selectively...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/cbf1821b71684008af08a97dbb458eea |
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