Role of PET/CT in initial evaluation of lymphoma patients

Abstract Background Accurate radiologic assessment of treatment response in lymphoma patients is important to evaluate the effectiveness of treatment and consequently predict the relapse; the value of PET/CT for post-treatment prognosis prediction has been recently investigated. The aim of this stud...

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Autores principales:	Manar Mohamed Naguib, Samer Malak Botros, Amir Louis Louka, Rasha S. Hussein
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Hodgkin lymphoma Non-Hodgkin lymphoma 18F FDG PET/CT PERCIST CMR PMR Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/cbf6d16394974d4a81a953c1c607609a
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spelling	oai:doaj.org-article:cbf6d16394974d4a81a953c1c607609a2021-12-05T12:17:27ZRole of PET/CT in initial evaluation of lymphoma patients10.1186/s43055-021-00670-32090-4762https://doaj.org/article/cbf6d16394974d4a81a953c1c607609a2021-12-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00670-3https://doaj.org/toc/2090-4762Abstract Background Accurate radiologic assessment of treatment response in lymphoma patients is important to evaluate the effectiveness of treatment and consequently predict the relapse; the value of PET/CT for post-treatment prognosis prediction has been recently investigated. The aim of this study is to highlight the prognostic value of PET-CT metabolic volumetric parameters in the evaluation of lymphoma patients. Results Among the included 40 patients, post-treatment SUV, MTV, and TLG were significantly lower in a responsive group than the non-responsive group. % changes of all quantitative PET/CT parameters were significantly higher in the responsive group than the non-responsive group. Conclusions This study suggests that pre-treatment PET/CT quantitative measures (except baseline SUVmax) are not conclusive in the prediction of patient response to treatment; however, the ΔSUVmax, ΔMTV, and ΔTLG% from the baseline to the end of therapy could be used in predicting patient response to treatment, determining patient prognosis, and suggesting the relapse.Manar Mohamed NaguibSamer Malak BotrosAmir Louis LoukaRasha S. HusseinSpringerOpenarticleHodgkin lymphomaNon-Hodgkin lymphoma18F FDG PET/CTPERCISTCMRPMRMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hodgkin lymphoma Non-Hodgkin lymphoma 18F FDG PET/CT PERCIST CMR PMR Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Hodgkin lymphoma Non-Hodgkin lymphoma 18F FDG PET/CT PERCIST CMR PMR Medical physics. Medical radiology. Nuclear medicine R895-920 Manar Mohamed Naguib Samer Malak Botros Amir Louis Louka Rasha S. Hussein Role of PET/CT in initial evaluation of lymphoma patients
description	Abstract Background Accurate radiologic assessment of treatment response in lymphoma patients is important to evaluate the effectiveness of treatment and consequently predict the relapse; the value of PET/CT for post-treatment prognosis prediction has been recently investigated. The aim of this study is to highlight the prognostic value of PET-CT metabolic volumetric parameters in the evaluation of lymphoma patients. Results Among the included 40 patients, post-treatment SUV, MTV, and TLG were significantly lower in a responsive group than the non-responsive group. % changes of all quantitative PET/CT parameters were significantly higher in the responsive group than the non-responsive group. Conclusions This study suggests that pre-treatment PET/CT quantitative measures (except baseline SUVmax) are not conclusive in the prediction of patient response to treatment; however, the ΔSUVmax, ΔMTV, and ΔTLG% from the baseline to the end of therapy could be used in predicting patient response to treatment, determining patient prognosis, and suggesting the relapse.
format	article
author	Manar Mohamed Naguib Samer Malak Botros Amir Louis Louka Rasha S. Hussein
author_facet	Manar Mohamed Naguib Samer Malak Botros Amir Louis Louka Rasha S. Hussein
author_sort	Manar Mohamed Naguib
title	Role of PET/CT in initial evaluation of lymphoma patients
title_short	Role of PET/CT in initial evaluation of lymphoma patients
title_full	Role of PET/CT in initial evaluation of lymphoma patients
title_fullStr	Role of PET/CT in initial evaluation of lymphoma patients
title_full_unstemmed	Role of PET/CT in initial evaluation of lymphoma patients
title_sort	role of pet/ct in initial evaluation of lymphoma patients
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/cbf6d16394974d4a81a953c1c607609a
work_keys_str_mv	AT manarmohamednaguib roleofpetctininitialevaluationoflymphomapatients AT samermalakbotros roleofpetctininitialevaluationoflymphomapatients AT amirlouislouka roleofpetctininitialevaluationoflymphomapatients AT rashashussein roleofpetctininitialevaluationoflymphomapatients
_version_	1718372103672037376

Role of PET/CT in initial evaluation of lymphoma patients

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