An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

The involvement of long non-coding RNA (lncRNA) in the regulation of N6-methyladenosine (m6A) modification of RNA is unclear. Here, the authors show that LINC00266-1 encodes a peptide that binds to m6A reader, IGF2BP1 to enhance the recognition of m6A modified RNA transcripts and increase their stab...

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Autores principales: Song Zhu, Ji-Zhong Wang, De Chen, Yu-Tian He, Nan Meng, Min Chen, Rui-Xun Lu, Xin-Hui Chen, Xiao-Lan Zhang, Guang-Rong Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/cbf7c7701ca6452e9eff7957bef4b3e5
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