CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS

Abstract. Application of flow cytometry (FC) techniques has considerably expanded the opportunities for evaluation of immune cells, aiming for better diagnostics of immunodeficiency disorders, autoimmune and lymphoproliferative diseases, etc.A procedure of laboratory testing is subdivided into sever...

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Autores principales:	L. V. Serebrovskaya, L. A. Ivanova, S. V. Khaidukov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	flow cytometry immunophenotyping pre-analytical stage Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/cc008cfeb7c04108a67434bff1b1a453
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spelling	oai:doaj.org-article:cc008cfeb7c04108a67434bff1b1a4532021-11-18T08:03:43ZCHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS1563-06252313-741X10.15789/1563-0625-2011-6-639-646https://doaj.org/article/cc008cfeb7c04108a67434bff1b1a4532014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/594https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Application of flow cytometry (FC) techniques has considerably expanded the opportunities for evaluation of immune cells, aiming for better diagnostics of immunodeficiency disorders, autoimmune and lymphoproliferative diseases, etc.A procedure of laboratory testing is subdivided into several stages, i.e., pre-analytical, analytical and post-analytical. At present, some strict criteria are developed for inclusion of various cell parameters into a diagnostic set, along with operational algorithms, in order to optimize the FC procedures. However, the percentage of errors in FC assays still remains high. More than a half of the errors originate from pre-analytical stage.The recommendations listed in this article should definitely influence quality of laboratory investigations and improve diagnostics of immune functional disorders, thus providing adequacy of therapeutic prescriptions. (Med. Immunol., 2011, vol. 13, N 6, pp 639-646)L. V. SerebrovskayaL. A. IvanovaS. V. KhaidukovSPb RAACIarticleflow cytometryimmunophenotypingpre-analytical stageImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 6, Pp 639-646 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	flow cytometry immunophenotyping pre-analytical stage Immunologic diseases. Allergy RC581-607
spellingShingle	flow cytometry immunophenotyping pre-analytical stage Immunologic diseases. Allergy RC581-607 L. V. Serebrovskaya L. A. Ivanova S. V. Khaidukov CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
description	Abstract. Application of flow cytometry (FC) techniques has considerably expanded the opportunities for evaluation of immune cells, aiming for better diagnostics of immunodeficiency disorders, autoimmune and lymphoproliferative diseases, etc.A procedure of laboratory testing is subdivided into several stages, i.e., pre-analytical, analytical and post-analytical. At present, some strict criteria are developed for inclusion of various cell parameters into a diagnostic set, along with operational algorithms, in order to optimize the FC procedures. However, the percentage of errors in FC assays still remains high. More than a half of the errors originate from pre-analytical stage.The recommendations listed in this article should definitely influence quality of laboratory investigations and improve diagnostics of immune functional disorders, thus providing adequacy of therapeutic prescriptions. (Med. Immunol., 2011, vol. 13, N 6, pp 639-646)
format	article
author	L. V. Serebrovskaya L. A. Ivanova S. V. Khaidukov
author_facet	L. V. Serebrovskaya L. A. Ivanova S. V. Khaidukov
author_sort	L. V. Serebrovskaya
title	CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
title_short	CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
title_full	CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
title_fullStr	CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
title_full_unstemmed	CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS
title_sort	characteristics of pre-analytical stage in immunophenotyping of peripheral blood cells
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/cc008cfeb7c04108a67434bff1b1a453
work_keys_str_mv	AT lvserebrovskaya characteristicsofpreanalyticalstageinimmunophenotypingofperipheralbloodcells AT laivanova characteristicsofpreanalyticalstageinimmunophenotypingofperipheralbloodcells AT svkhaidukov characteristicsofpreanalyticalstageinimmunophenotypingofperipheralbloodcells
_version_	1718422447460450304

CHARACTERISTICS OF PRE-ANALYTICAL STAGE IN IMMUNOPHENOTYPING OF PERIPHERAL BLOOD CELLS

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