Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice

Deep-brain stimulation ameliorates parkinsonian symptoms, but it usually requires permanent implantation of hardware and connectors. Here, the authors show magnetothermal neuromodulation through the activation of TRPV1 can improve locomotor deficits in mouse models of Parkinson’s disease.

Guardado en:

Detalles Bibliográficos
Autores principales:	Sarah-Anna Hescham, Po-Han Chiang, Danijela Gregurec, Junsang Moon, Michael G. Christiansen, Ali Jahanshahi, Huajie Liu, Dekel Rosenfeld, Arnd Pralle, Polina Anikeeva, Yasin Temel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cc0214f3cc124799a505d0f71c4d4d68
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cc0214f3cc124799a505d0f71c4d4d68
record_format	dspace
spelling	oai:doaj.org-article:cc0214f3cc124799a505d0f71c4d4d682021-12-02T17:27:04ZMagnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice10.1038/s41467-021-25837-42041-1723https://doaj.org/article/cc0214f3cc124799a505d0f71c4d4d682021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25837-4https://doaj.org/toc/2041-1723Deep-brain stimulation ameliorates parkinsonian symptoms, but it usually requires permanent implantation of hardware and connectors. Here, the authors show magnetothermal neuromodulation through the activation of TRPV1 can improve locomotor deficits in mouse models of Parkinson’s disease.Sarah-Anna HeschamPo-Han ChiangDanijela GregurecJunsang MoonMichael G. ChristiansenAli JahanshahiHuajie LiuDekel RosenfeldArnd PrallePolina AnikeevaYasin TemelNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah-Anna Hescham Po-Han Chiang Danijela Gregurec Junsang Moon Michael G. Christiansen Ali Jahanshahi Huajie Liu Dekel Rosenfeld Arnd Pralle Polina Anikeeva Yasin Temel Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
description	Deep-brain stimulation ameliorates parkinsonian symptoms, but it usually requires permanent implantation of hardware and connectors. Here, the authors show magnetothermal neuromodulation through the activation of TRPV1 can improve locomotor deficits in mouse models of Parkinson’s disease.
format	article
author	Sarah-Anna Hescham Po-Han Chiang Danijela Gregurec Junsang Moon Michael G. Christiansen Ali Jahanshahi Huajie Liu Dekel Rosenfeld Arnd Pralle Polina Anikeeva Yasin Temel
author_facet	Sarah-Anna Hescham Po-Han Chiang Danijela Gregurec Junsang Moon Michael G. Christiansen Ali Jahanshahi Huajie Liu Dekel Rosenfeld Arnd Pralle Polina Anikeeva Yasin Temel
author_sort	Sarah-Anna Hescham
title	Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
title_short	Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
title_full	Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
title_fullStr	Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
title_full_unstemmed	Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
title_sort	magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cc0214f3cc124799a505d0f71c4d4d68
work_keys_str_mv	AT sarahannahescham magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT pohanchiang magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT danijelagregurec magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT junsangmoon magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT michaelgchristiansen magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT alijahanshahi magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT huajieliu magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT dekelrosenfeld magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT arndpralle magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT polinaanikeeva magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice AT yasintemel magnetothermalnanoparticletechnologyalleviatesparkinsonianlikesymptomsinmice
_version_	1718380813117030400

Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice

Ejemplares similares