Influences on rebubble rate in Descemet's membrane endothelial keratoplasty

Keegan B Mechels,1 Michael D Greenwood,2 Ramu G Sudhagoni,3 John P Berdahl2 1Sanford School of Medicine, University of South Dakota, Vermillion, SD, 2Vance Thompson Vision, Sioux Falls, SD, 3School of Health Sciences, University of South Dakota, Vermillion, SD, USA Purpose: Descemet’s me...

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Autores principales: Mechels KB, Greenwood MD, Sudhagoni RG, Berdahl JP
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Publicado: Dove Medical Press 2017
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spelling oai:doaj.org-article:cc10f81145c84a5c98308ba3c0e46fa52021-12-02T06:11:15ZInfluences on rebubble rate in Descemet's membrane endothelial keratoplasty1177-5483https://doaj.org/article/cc10f81145c84a5c98308ba3c0e46fa52017-12-01T00:00:00Zhttps://www.dovepress.com/influences-on-rebubble-rate-in-descemets-membrane-endothelial-keratopl-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Keegan B Mechels,1 Michael D Greenwood,2 Ramu G Sudhagoni,3 John P Berdahl2 1Sanford School of Medicine, University of South Dakota, Vermillion, SD, 2Vance Thompson Vision, Sioux Falls, SD, 3School of Health Sciences, University of South Dakota, Vermillion, SD, USA Purpose: Descemet’s membrane endothelial keratoplasty (DMEK) is a minimally invasive partial corneal transplant procedure used in patients with failing endothelial membranes. This study aims to identify those factors which influence the need for a rebubble of the corneal graft. Methods: A total of 94 eyes that received DMEK between March 2014 and January 2016 at Vance Thompson Vision were used in the study. Demographic and graft data were collected from the patients and donors, and perioperative statistics of the procedures. A logistical regression was used to compare eyes that did and did not require a rebubble. Results: Among those characteristics that were included (patient age/sex, donor age/sex, death to processing time, donation to surgery time, death to procurement time, specular cell count density, burping procedure, postoperative day 1 intraocular pressure [IOP], and postoperative week 1 IOP, concurrent phacoemulsification, and how well the Descemet graft was centered), only a lower specular cell count density of the corneal graft, and a graft that was not well-centered correlated with needing a rebubble due to partial graft detachment (p=0.021) and (p=0.023), respectively. Conclusion: An increased specular cell count density may allow for better placement of the corneal graft by allowing for better unfolding in DMEK procedures. A well-centered graft may decrease postoperative complications by increasing adherence. Additionally, postoperative management of IOP may not affect the rebubble rate, and therefore should be left to the discretion of the provider to determine whether it is necessary. Keywords: descemet, rebubble, keratoplasty, DMEKMechels KBGreenwood MDSudhagoni RGBerdahl JPDove Medical PressarticleDescemetrebubblekeratoplastyDMEKOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 2139-2144 (2017)
institution DOAJ
collection DOAJ
language EN
topic Descemet
rebubble
keratoplasty
DMEK
Ophthalmology
RE1-994
spellingShingle Descemet
rebubble
keratoplasty
DMEK
Ophthalmology
RE1-994
Mechels KB
Greenwood MD
Sudhagoni RG
Berdahl JP
Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
description Keegan B Mechels,1 Michael D Greenwood,2 Ramu G Sudhagoni,3 John P Berdahl2 1Sanford School of Medicine, University of South Dakota, Vermillion, SD, 2Vance Thompson Vision, Sioux Falls, SD, 3School of Health Sciences, University of South Dakota, Vermillion, SD, USA Purpose: Descemet’s membrane endothelial keratoplasty (DMEK) is a minimally invasive partial corneal transplant procedure used in patients with failing endothelial membranes. This study aims to identify those factors which influence the need for a rebubble of the corneal graft. Methods: A total of 94 eyes that received DMEK between March 2014 and January 2016 at Vance Thompson Vision were used in the study. Demographic and graft data were collected from the patients and donors, and perioperative statistics of the procedures. A logistical regression was used to compare eyes that did and did not require a rebubble. Results: Among those characteristics that were included (patient age/sex, donor age/sex, death to processing time, donation to surgery time, death to procurement time, specular cell count density, burping procedure, postoperative day 1 intraocular pressure [IOP], and postoperative week 1 IOP, concurrent phacoemulsification, and how well the Descemet graft was centered), only a lower specular cell count density of the corneal graft, and a graft that was not well-centered correlated with needing a rebubble due to partial graft detachment (p=0.021) and (p=0.023), respectively. Conclusion: An increased specular cell count density may allow for better placement of the corneal graft by allowing for better unfolding in DMEK procedures. A well-centered graft may decrease postoperative complications by increasing adherence. Additionally, postoperative management of IOP may not affect the rebubble rate, and therefore should be left to the discretion of the provider to determine whether it is necessary. Keywords: descemet, rebubble, keratoplasty, DMEK
format article
author Mechels KB
Greenwood MD
Sudhagoni RG
Berdahl JP
author_facet Mechels KB
Greenwood MD
Sudhagoni RG
Berdahl JP
author_sort Mechels KB
title Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
title_short Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
title_full Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
title_fullStr Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
title_full_unstemmed Influences on rebubble rate in Descemet's membrane endothelial keratoplasty
title_sort influences on rebubble rate in descemet's membrane endothelial keratoplasty
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/cc10f81145c84a5c98308ba3c0e46fa5
work_keys_str_mv AT mechelskb influencesonrebubblerateindescemet39smembraneendothelialkeratoplasty
AT greenwoodmd influencesonrebubblerateindescemet39smembraneendothelialkeratoplasty
AT sudhagonirg influencesonrebubblerateindescemet39smembraneendothelialkeratoplasty
AT berdahljp influencesonrebubblerateindescemet39smembraneendothelialkeratoplasty
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