Robust light–dark patterns and reduced amyloid load in an Alzheimer’s disease transgenic mouse model

Robust light–dark patterns and reduced amyloid load in an Alzheimer’s disease transgenic mouse model

Abstract Circadian disruption resulting from exposure to irregular light–dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer’s disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. br...

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Autores principales: Rohan Nagare, Bernard Possidente, Sarita Lagalwar, Mariana G. Figueiro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/cc14f28708994586990708e7d9e1fb40
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