Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice
Following peripheral nerve injury, influx of immune cells to the site may contribute to the development of chronic pain. Here the authors show that TRPA1 is expressed on Schwann cells and contributes to immune cell influx in a mouse model of neuropathic pain.
Enregistré dans:
Auteurs principaux: | Francesco De Logu, Romina Nassini, Serena Materazzi, Muryel Carvalho Gonçalves, Daniele Nosi, Duccio Rossi Degl’Innocenti, Ilaria M. Marone, Juliano Ferreira, Simone Li Puma, Silvia Benemei, Gabriela Trevisan, Daniel Souza Monteiro de Araújo, Riccardo Patacchini, Nigel W. Bunnett, Pierangelo Geppetti |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/cc21242beb744e37aeabdb35c1c9899c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The TRPA1 Channel Amplifies the Oxidative Stress Signal in Melanoma
par: Francesco De Logu, et autres
Publié: (2021) -
The analgesic effect on neuropathic pain of retrogradely transported botulinum neurotoxin A involves Schwann cells and astrocytes.
par: Sara Marinelli, et autres
Publié: (2012) -
A protein-coated micro-sucker patch inspired by octopus for adhesion in wet conditions
par: Gabriella Meloni, et autres
Publié: (2020) -
Tunable polarization-induced Fano resonances in stacked wire-grid metasurfaces
par: Xavier Romain, et autres
Publié: (2021) -
Polyglutamine repeats are associated to specific sequence biases that are conserved among eukaryotes.
par: Matteo Ramazzotti, et autres
Publié: (2012)