Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame

Sesame seeds contain phenylpropanoid-derived lignans that are potentially beneficial to human health. Here, the authors clone a cytochrome P450 enzyme that is responsible for the last steps of sesame lignan biosynthesis and show that it acts through a novel oxidative rearrangement mechanism.

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Autores principales:	Jun Murata, Eiichiro Ono, Seigo Yoroizuka, Hiromi Toyonaga, Akira Shiraishi, Shoko Mori, Masayuki Tera, Toshiaki Azuma, Atsushi J. Nagano, Masaru Nakayasu, Masaharu Mizutani, Tatsuya Wakasugi, Masayuki P. Yamamoto, Manabu Horikawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cc2cb41dc344450680c9fa01de78147d
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spelling	oai:doaj.org-article:cc2cb41dc344450680c9fa01de78147d2021-12-02T14:42:17ZOxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame10.1038/s41467-017-02053-72041-1723https://doaj.org/article/cc2cb41dc344450680c9fa01de78147d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02053-7https://doaj.org/toc/2041-1723Sesame seeds contain phenylpropanoid-derived lignans that are potentially beneficial to human health. Here, the authors clone a cytochrome P450 enzyme that is responsible for the last steps of sesame lignan biosynthesis and show that it acts through a novel oxidative rearrangement mechanism.Jun MurataEiichiro OnoSeigo YoroizukaHiromi ToyonagaAkira ShiraishiShoko MoriMasayuki TeraToshiaki AzumaAtsushi J. NaganoMasaru NakayasuMasaharu MizutaniTatsuya WakasugiMasayuki P. YamamotoManabu HorikawaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jun Murata Eiichiro Ono Seigo Yoroizuka Hiromi Toyonaga Akira Shiraishi Shoko Mori Masayuki Tera Toshiaki Azuma Atsushi J. Nagano Masaru Nakayasu Masaharu Mizutani Tatsuya Wakasugi Masayuki P. Yamamoto Manabu Horikawa Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
description	Sesame seeds contain phenylpropanoid-derived lignans that are potentially beneficial to human health. Here, the authors clone a cytochrome P450 enzyme that is responsible for the last steps of sesame lignan biosynthesis and show that it acts through a novel oxidative rearrangement mechanism.
format	article
author	Jun Murata Eiichiro Ono Seigo Yoroizuka Hiromi Toyonaga Akira Shiraishi Shoko Mori Masayuki Tera Toshiaki Azuma Atsushi J. Nagano Masaru Nakayasu Masaharu Mizutani Tatsuya Wakasugi Masayuki P. Yamamoto Manabu Horikawa
author_facet	Jun Murata Eiichiro Ono Seigo Yoroizuka Hiromi Toyonaga Akira Shiraishi Shoko Mori Masayuki Tera Toshiaki Azuma Atsushi J. Nagano Masaru Nakayasu Masaharu Mizutani Tatsuya Wakasugi Masayuki P. Yamamoto Manabu Horikawa
author_sort	Jun Murata
title	Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
title_short	Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
title_full	Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
title_fullStr	Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
title_full_unstemmed	Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame
title_sort	oxidative rearrangement of (+)-sesamin by cyp92b14 co-generates twin dietary lignans in sesame
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/cc2cb41dc344450680c9fa01de78147d
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Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame

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