Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

Asymmetric subcellular mRNA distribution is important for local translation of neuronal mRNAs. Here the authors employed MS2 live-cell imaging and showed that the reporter mRNA containing the 3’ UTR of Rgs4 shows an anterograde transport bias, dependent on neuronal activity and the protein Staufen2,...

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Bibliographic Details
Main Authors: Karl E. Bauer, Inmaculada Segura, Imre Gaspar, Volker Scheuss, Christin Illig, Georg Ammer, Saskia Hutten, Eugénia Basyuk, Sandra M. Fernández-Moya, Janina Ehses, Edouard Bertrand, Michael A. Kiebler
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/cc4d41928ef64ea9ba34f9e96c74913b
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https://doaj.org/article/cc4d41928ef64ea9ba34f9e96c74913b

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