Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.

<h4>Background</h4>Cigarette smoking, hypertension, dyslipidemia, diabetes, and obesity are conventional risk factors (RFs) for coronary artery disease (CAD). Population trends for these RFs have varied in recent decades. Consequently, the risk factor profile for patients presenting with...

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Autores principales:	Zoya Gurm, Milan Seth, Edouard Daher, Elizabeth Pielsticker, M Imran Qureshi, Mark Zainea, Michael Tucciarone, George Hanzel, Peter K Henke, Devraj Sukul
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cc558f60bd974ab190cd882831b1f1a9
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spelling	oai:doaj.org-article:cc558f60bd974ab190cd882831b1f1a92021-12-02T20:10:55ZPrevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.1932-620310.1371/journal.pone.0250801https://doaj.org/article/cc558f60bd974ab190cd882831b1f1a92021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0250801https://doaj.org/toc/1932-6203<h4>Background</h4>Cigarette smoking, hypertension, dyslipidemia, diabetes, and obesity are conventional risk factors (RFs) for coronary artery disease (CAD). Population trends for these RFs have varied in recent decades. Consequently, the risk factor profile for patients presenting with a new diagnosis of CAD in contemporary practice remains unknown.<h4>Objectives</h4>To examine the prevalence of RFs and their temporal trends among patients without a history of myocardial infarction or revascularization who underwent their first percutaneous coronary intervention (PCI).<h4>Methods</h4>We examined the prevalence and temporal trends of RFs among patients without a history of prior myocardial infarction, PCI, or coronary artery bypass graft surgery who underwent PCI at 47 non-federal hospitals in Michigan between 1/1/2010 and 3/31/2018.<h4>Results</h4>Of 69,571 men and 38,930 women in the study cohort, 95.5% of patients had 1 or more RFs and nearly half (55.2% of women and 48.7% of men) had ≥3 RFs. The gap in the mean age at the time of presentation between men and women narrowed as the number of RFs increased with a gap of 6 years among those with 2 RFs to <1 year among those with 5 RFs. Compared with patients without a current/recent history of smoking, those with a current/recent history of smoking presented a decade earlier (age 56.8 versus 66.9 years; p <0.0001). Compared with patients without obesity, patients with obesity presented 4.0 years earlier (age 61.4 years versus 65.4 years; p <0.0001).<h4>Conclusions</h4>Modifiable RFs are widely prevalent among patients undergoing their first PCI. Smoking and obesity are associated with an earlier age of presentation. Population-level interventions aimed at preventing obesity and smoking could significantly delay the onset of CAD and the need for PCI.Zoya GurmMilan SethEdouard DaherElizabeth PielstickerM Imran QureshiMark ZaineaMichael TucciaroneGeorge HanzelPeter K HenkeDevraj SukulPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0250801 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Zoya Gurm Milan Seth Edouard Daher Elizabeth Pielsticker M Imran Qureshi Mark Zainea Michael Tucciarone George Hanzel Peter K Henke Devraj Sukul Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
description	<h4>Background</h4>Cigarette smoking, hypertension, dyslipidemia, diabetes, and obesity are conventional risk factors (RFs) for coronary artery disease (CAD). Population trends for these RFs have varied in recent decades. Consequently, the risk factor profile for patients presenting with a new diagnosis of CAD in contemporary practice remains unknown.<h4>Objectives</h4>To examine the prevalence of RFs and their temporal trends among patients without a history of myocardial infarction or revascularization who underwent their first percutaneous coronary intervention (PCI).<h4>Methods</h4>We examined the prevalence and temporal trends of RFs among patients without a history of prior myocardial infarction, PCI, or coronary artery bypass graft surgery who underwent PCI at 47 non-federal hospitals in Michigan between 1/1/2010 and 3/31/2018.<h4>Results</h4>Of 69,571 men and 38,930 women in the study cohort, 95.5% of patients had 1 or more RFs and nearly half (55.2% of women and 48.7% of men) had ≥3 RFs. The gap in the mean age at the time of presentation between men and women narrowed as the number of RFs increased with a gap of 6 years among those with 2 RFs to <1 year among those with 5 RFs. Compared with patients without a current/recent history of smoking, those with a current/recent history of smoking presented a decade earlier (age 56.8 versus 66.9 years; p <0.0001). Compared with patients without obesity, patients with obesity presented 4.0 years earlier (age 61.4 years versus 65.4 years; p <0.0001).<h4>Conclusions</h4>Modifiable RFs are widely prevalent among patients undergoing their first PCI. Smoking and obesity are associated with an earlier age of presentation. Population-level interventions aimed at preventing obesity and smoking could significantly delay the onset of CAD and the need for PCI.
format	article
author	Zoya Gurm Milan Seth Edouard Daher Elizabeth Pielsticker M Imran Qureshi Mark Zainea Michael Tucciarone George Hanzel Peter K Henke Devraj Sukul
author_facet	Zoya Gurm Milan Seth Edouard Daher Elizabeth Pielsticker M Imran Qureshi Mark Zainea Michael Tucciarone George Hanzel Peter K Henke Devraj Sukul
author_sort	Zoya Gurm
title	Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
title_short	Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
title_full	Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
title_fullStr	Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
title_full_unstemmed	Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.
title_sort	prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: implications for primary prevention.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/cc558f60bd974ab190cd882831b1f1a9
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Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention.

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