Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells

Here, using human cells and mouse models, the authors show that Zika virus can infect preimplantation trophectoderm. Pre-implantation infection can affect nervous system development and survival of neural progenitors, and can result in miscarriage or spontaneous abortion.

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Detalles Bibliográficos
Autores principales: Lei Tan, Lauretta A. Lacko, Ting Zhou, Delia Tomoiaga, Romulo Hurtado, Tuo Zhang, Ana Sevilla, Aaron Zhong, Christopher E Mason, Scott Noggle, Todd Evans, Heidi Stuhlmann, Robert E. Schwartz, Shuibing Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cc5622b5dfc04f5d988bdfabb453be0c
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