Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin

Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin

Dominik Samotij,1 Ewelina Gawron,1 Justyna Szczęch,1 Elżbieta Ostańska,2 Adam Reich1 1Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland; 2Department of Pathology, Institute of Medical Sciences, Medical College of Rzeszow Unive...

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Autores principales: Samotij D, Gawron E, Szczęch J, Ostańska E, Reich A
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
Materias:
psoriasis
pustular psoriasis
biologics
biologic therapy
sars-cov-2
coronavirus
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/cc5a28bb27384048a481c675fbd8602c
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spelling oai:doaj.org-article:cc5a28bb27384048a481c675fbd8602c2021-12-02T16:44:46ZAcrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin1177-5491https://doaj.org/article/cc5a28bb27384048a481c675fbd8602c2021-04-01T00:00:00Zhttps://www.dovepress.com/acrodermatitis-continua-of-hallopeau-evolving-into-generalized-pustula-peer-reviewed-fulltext-article-BTThttps://doaj.org/toc/1177-5491Dominik Samotij,1 Ewelina Gawron,1 Justyna Szczęch,1 Elżbieta Ostańska,2 Adam Reich1 1Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland; 2Department of Pathology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, PolandCorrespondence: Adam ReichDepartment of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, ul. Fryderyka Szopena 2, Rzeszów, 35-055, PolandTel +48 605076722Fax +48 17 8666294Email adamandrzejreich@gmail.comAbstract: The global pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging. Various cutaneous manifestations have been observed in patients with SARS-CoV-2 infection, yet exacerbations of psoriasis have been reported sporadically. Acrodermatitis continua of Hallopeau (ACH) is an uncommon, sterile pustular dermatosis involving one or more digits. In some rare cases, ACH may evolve into generalized pustular psoriasis (GPP), which is a severe, and potentially life-threatening, form of psoriasis that manifests itself with widespread eruptions of pustules. We describe the first case of a patient in whom ACH abruptly progressed into GPP during COVID-19. A combination of infliximab and acitretin was used allowing swift clinical improvement.Keywords: psoriasis, pustular psoriasis, biologics, biologic therapy, SARS-CoV-2, coronavirusSamotij DGawron ESzczęch JOstańska EReich ADove Medical Pressarticlepsoriasispustular psoriasisbiologicsbiologic therapysars-cov-2coronavirusMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol Volume 15, Pp 107-113 (2021)
institution DOAJ
collection DOAJ
language EN
topic psoriasis
pustular psoriasis
biologics
biologic therapy
sars-cov-2
coronavirus
Medicine (General)
R5-920
spellingShingle psoriasis
pustular psoriasis
biologics
biologic therapy
sars-cov-2
coronavirus
Medicine (General)
R5-920
Samotij D
Gawron E
Szczęch J
Ostańska E
Reich A
Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
description Dominik Samotij,1 Ewelina Gawron,1 Justyna Szczęch,1 Elżbieta Ostańska,2 Adam Reich1 1Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland; 2Department of Pathology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, PolandCorrespondence: Adam ReichDepartment of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, ul. Fryderyka Szopena 2, Rzeszów, 35-055, PolandTel +48 605076722Fax +48 17 8666294Email adamandrzejreich@gmail.comAbstract: The global pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging. Various cutaneous manifestations have been observed in patients with SARS-CoV-2 infection, yet exacerbations of psoriasis have been reported sporadically. Acrodermatitis continua of Hallopeau (ACH) is an uncommon, sterile pustular dermatosis involving one or more digits. In some rare cases, ACH may evolve into generalized pustular psoriasis (GPP), which is a severe, and potentially life-threatening, form of psoriasis that manifests itself with widespread eruptions of pustules. We describe the first case of a patient in whom ACH abruptly progressed into GPP during COVID-19. A combination of infliximab and acitretin was used allowing swift clinical improvement.Keywords: psoriasis, pustular psoriasis, biologics, biologic therapy, SARS-CoV-2, coronavirus
format article
author Samotij D
Gawron E
Szczęch J
Ostańska E
Reich A
author_facet Samotij D
Gawron E
Szczęch J
Ostańska E
Reich A
author_sort Samotij D
title Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
title_short Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
title_full Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
title_fullStr Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
title_full_unstemmed Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
title_sort acrodermatitis continua of hallopeau evolving into generalized pustular psoriasis following covid‐19: a case report of a successful treatment with infliximab in combination with acitretin
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/cc5a28bb27384048a481c675fbd8602c
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