Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report

A collision tumor is composed of two adjacent histological distinct neoplasms without the histological admixture of cell types in the same organ or tissue. It is rare in pancreas. Herein we report an unusual case of a mixed malignant neuroendocrine tumor (NET) and ductal adenocarcinoma of pancreas i...

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Autores principales:	Prajna Das, Ranjita Panigrahi, Prita Pradhan, Urmila Senapati, Mihir Kumar Mohapatra
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	collision tumor ductal adenocarcinoma neuroendocrine tumor ihc Pathology RB1-214 Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/cc5e289d9ca34ca480df3555e20f2109
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spelling	oai:doaj.org-article:cc5e289d9ca34ca480df3555e20f21092021-12-02T17:49:11ZPancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report0377-492910.4103/IJPM.IJPM_735_19https://doaj.org/article/cc5e289d9ca34ca480df3555e20f21092021-01-01T00:00:00Zhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=172;epage=174;aulast=Dashttps://doaj.org/toc/0377-4929A collision tumor is composed of two adjacent histological distinct neoplasms without the histological admixture of cell types in the same organ or tissue. It is rare in pancreas. Herein we report an unusual case of a mixed malignant neuroendocrine tumor (NET) and ductal adenocarcinoma of pancreas in a 24 year old male who presented with history abdomen pain. A clinicoradiological diagnosis of chronic calcific pancreatitis with carcinoma body of pancreas was made. Distal pancreaticosplenectomy specimen showed a grey white, nodular growth measuring 2 x 2 x 1.2 cm on the cut surface of pancreas. Histopathology revealed a composite tumor consisting of ductal and neuroendocrine origin. Immunohistochemistry showed complementary staining for CK7 in adenocarcinoma and chromogranin A in NET areas confirming a collision tumor. Accurate evaluation of the radiologic pointers, histomorphologic evaluation to recognize and quantitate the individual components, appropriate immunohistochemical evaluation and correlation is essential for diagnosis.Prajna DasRanjita PanigrahiPrita PradhanUrmila SenapatiMihir Kumar MohapatraWolters Kluwer Medknow Publicationsarticlecollision tumorductal adenocarcinomaneuroendocrine tumorihcPathologyRB1-214MicrobiologyQR1-502ENIndian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 172-174 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	collision tumor ductal adenocarcinoma neuroendocrine tumor ihc Pathology RB1-214 Microbiology QR1-502
spellingShingle	collision tumor ductal adenocarcinoma neuroendocrine tumor ihc Pathology RB1-214 Microbiology QR1-502 Prajna Das Ranjita Panigrahi Prita Pradhan Urmila Senapati Mihir Kumar Mohapatra Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
description	A collision tumor is composed of two adjacent histological distinct neoplasms without the histological admixture of cell types in the same organ or tissue. It is rare in pancreas. Herein we report an unusual case of a mixed malignant neuroendocrine tumor (NET) and ductal adenocarcinoma of pancreas in a 24 year old male who presented with history abdomen pain. A clinicoradiological diagnosis of chronic calcific pancreatitis with carcinoma body of pancreas was made. Distal pancreaticosplenectomy specimen showed a grey white, nodular growth measuring 2 x 2 x 1.2 cm on the cut surface of pancreas. Histopathology revealed a composite tumor consisting of ductal and neuroendocrine origin. Immunohistochemistry showed complementary staining for CK7 in adenocarcinoma and chromogranin A in NET areas confirming a collision tumor. Accurate evaluation of the radiologic pointers, histomorphologic evaluation to recognize and quantitate the individual components, appropriate immunohistochemical evaluation and correlation is essential for diagnosis.
format	article
author	Prajna Das Ranjita Panigrahi Prita Pradhan Urmila Senapati Mihir Kumar Mohapatra
author_facet	Prajna Das Ranjita Panigrahi Prita Pradhan Urmila Senapati Mihir Kumar Mohapatra
author_sort	Prajna Das
title	Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
title_short	Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
title_full	Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
title_fullStr	Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
title_full_unstemmed	Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report
title_sort	pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—a rare case report
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/cc5e289d9ca34ca480df3555e20f2109
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Pancreatic collision tumor of ductal adenocarcinoma and neuroendocrine tumor—A rare case report

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