Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes

Background: The need to provide a comparative analysis of corneal parameter changes compared to their preoperative values between Descemet membrane endothelial keratoplasty (DMEK) and ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) patients. Methods: The study included 24...

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Autores principales:	Anna Machalińska, Agnieszka Kuligowska, Bogna Kowalska, Krzysztof Safranow
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	UT-DSAEK DMEK keratometry astigmatism HOA Medicine R
Acceso en línea:	https://doaj.org/article/cc5ee27380854941b4e6b191e84919f4
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spelling	oai:doaj.org-article:cc5ee27380854941b4e6b191e84919f42021-11-11T17:44:23ZComparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes10.3390/jcm102151192077-0383https://doaj.org/article/cc5ee27380854941b4e6b191e84919f42021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5119https://doaj.org/toc/2077-0383Background: The need to provide a comparative analysis of corneal parameter changes compared to their preoperative values between Descemet membrane endothelial keratoplasty (DMEK) and ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) patients. Methods: The study included 24 eyes after UT-DSAEK and 24 eyes after DMEK. Visual acuity, endothelial cell count (ECC), central corneal thickness (CCT), mean keratometry (MK), mean astigmatism (MA), astigmatism asymmetry (AA) and higher-order aberrations (HOAs) were assessed at baseline and 1, 3, 6 and 12 months after the surgery. Results: From the 3rd month post operation, ECC was higher in the DMEK eyes than in the UT-DSAEK eyes (<i>p</i> = 0.01). In a bivariate analysis that was adjusted for age, DMEK was associated with a smaller decrease in posterior MK at the 1-month (β = −0.49, <i>p</i> = 0.002), 3-month (β = −0.50, <i>p</i> < 0.001), 6-month (β = −0.58, <i>p</i> < 0.001) and 12-month (β = −0.49, <i>p</i> < 0.001) follow-up visits. There were no significant differences in changes in anterior or combined surface MK throughout the observation period. Accordingly, no significant differences in changes in MA, AA or HOAs compared to the baseline values were identified between the eyes after DMEK and UT-DSAEK at any follow-up time point. Conclusions: UT-DSAEK seemed to be an easier and safer technique than DMEK while maintaining similar outcomes regarding irregular astigmatism and total keratometry values.Anna MachalińskaAgnieszka KuligowskaBogna KowalskaKrzysztof SafranowMDPI AGarticleUT-DSAEKDMEKkeratometryastigmatismHOAMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5119, p 5119 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	UT-DSAEK DMEK keratometry astigmatism HOA Medicine R
spellingShingle	UT-DSAEK DMEK keratometry astigmatism HOA Medicine R Anna Machalińska Agnieszka Kuligowska Bogna Kowalska Krzysztof Safranow Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
description	Background: The need to provide a comparative analysis of corneal parameter changes compared to their preoperative values between Descemet membrane endothelial keratoplasty (DMEK) and ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) patients. Methods: The study included 24 eyes after UT-DSAEK and 24 eyes after DMEK. Visual acuity, endothelial cell count (ECC), central corneal thickness (CCT), mean keratometry (MK), mean astigmatism (MA), astigmatism asymmetry (AA) and higher-order aberrations (HOAs) were assessed at baseline and 1, 3, 6 and 12 months after the surgery. Results: From the 3rd month post operation, ECC was higher in the DMEK eyes than in the UT-DSAEK eyes (<i>p</i> = 0.01). In a bivariate analysis that was adjusted for age, DMEK was associated with a smaller decrease in posterior MK at the 1-month (β = −0.49, <i>p</i> = 0.002), 3-month (β = −0.50, <i>p</i> < 0.001), 6-month (β = −0.58, <i>p</i> < 0.001) and 12-month (β = −0.49, <i>p</i> < 0.001) follow-up visits. There were no significant differences in changes in anterior or combined surface MK throughout the observation period. Accordingly, no significant differences in changes in MA, AA or HOAs compared to the baseline values were identified between the eyes after DMEK and UT-DSAEK at any follow-up time point. Conclusions: UT-DSAEK seemed to be an easier and safer technique than DMEK while maintaining similar outcomes regarding irregular astigmatism and total keratometry values.
format	article
author	Anna Machalińska Agnieszka Kuligowska Bogna Kowalska Krzysztof Safranow
author_facet	Anna Machalińska Agnieszka Kuligowska Bogna Kowalska Krzysztof Safranow
author_sort	Anna Machalińska
title	Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
title_short	Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
title_full	Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
title_fullStr	Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
title_full_unstemmed	Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes
title_sort	comparative analysis of corneal parameters in swept-source imaging between dmek and ut-dsaek eyes
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/cc5ee27380854941b4e6b191e84919f4
work_keys_str_mv	AT annamachalinska comparativeanalysisofcornealparametersinsweptsourceimagingbetweendmekandutdsaekeyes AT agnieszkakuligowska comparativeanalysisofcornealparametersinsweptsourceimagingbetweendmekandutdsaekeyes AT bognakowalska comparativeanalysisofcornealparametersinsweptsourceimagingbetweendmekandutdsaekeyes AT krzysztofsafranow comparativeanalysisofcornealparametersinsweptsourceimagingbetweendmekandutdsaekeyes
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Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes

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