Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protei...

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Autores principales: Tim Schneider, Lee-Hsueh Hung, Masood Aziz, Anna Wilmen, Stephanie Thaum, Jacqueline Wagner, Robert Janowski, Simon Müller, Silke Schreiner, Peter Friedhoff, Stefan Hüttelmaier, Dierk Niessing, Michael Sattler, Andreas Schlundt, Albrecht Bindereif
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cc6cce93f90546a49171482eb793687f
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spelling oai:doaj.org-article:cc6cce93f90546a49171482eb793687f2021-12-02T16:58:16ZCombinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP310.1038/s41467-019-09769-82041-1723https://doaj.org/article/cc6cce93f90546a49171482eb793687f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09769-8https://doaj.org/toc/2041-1723Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protein IMP3.Tim SchneiderLee-Hsueh HungMasood AzizAnna WilmenStephanie ThaumJacqueline WagnerRobert JanowskiSimon MüllerSilke SchreinerPeter FriedhoffStefan HüttelmaierDierk NiessingMichael SattlerAndreas SchlundtAlbrecht BindereifNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tim Schneider
Lee-Hsueh Hung
Masood Aziz
Anna Wilmen
Stephanie Thaum
Jacqueline Wagner
Robert Janowski
Simon Müller
Silke Schreiner
Peter Friedhoff
Stefan Hüttelmaier
Dierk Niessing
Michael Sattler
Andreas Schlundt
Albrecht Bindereif
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
description Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protein IMP3.
format article
author Tim Schneider
Lee-Hsueh Hung
Masood Aziz
Anna Wilmen
Stephanie Thaum
Jacqueline Wagner
Robert Janowski
Simon Müller
Silke Schreiner
Peter Friedhoff
Stefan Hüttelmaier
Dierk Niessing
Michael Sattler
Andreas Schlundt
Albrecht Bindereif
author_facet Tim Schneider
Lee-Hsueh Hung
Masood Aziz
Anna Wilmen
Stephanie Thaum
Jacqueline Wagner
Robert Janowski
Simon Müller
Silke Schreiner
Peter Friedhoff
Stefan Hüttelmaier
Dierk Niessing
Michael Sattler
Andreas Schlundt
Albrecht Bindereif
author_sort Tim Schneider
title Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
title_short Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
title_full Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
title_fullStr Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
title_full_unstemmed Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
title_sort combinatorial recognition of clustered rna elements by the multidomain rna-binding protein imp3
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/cc6cce93f90546a49171482eb793687f
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