Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protei...
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Nature Portfolio
2019
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oai:doaj.org-article:cc6cce93f90546a49171482eb793687f2021-12-02T16:58:16ZCombinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP310.1038/s41467-019-09769-82041-1723https://doaj.org/article/cc6cce93f90546a49171482eb793687f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09769-8https://doaj.org/toc/2041-1723Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protein IMP3.Tim SchneiderLee-Hsueh HungMasood AzizAnna WilmenStephanie ThaumJacqueline WagnerRobert JanowskiSimon MüllerSilke SchreinerPeter FriedhoffStefan HüttelmaierDierk NiessingMichael SattlerAndreas SchlundtAlbrecht BindereifNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019) |
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EN |
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Science Q |
spellingShingle |
Science Q Tim Schneider Lee-Hsueh Hung Masood Aziz Anna Wilmen Stephanie Thaum Jacqueline Wagner Robert Janowski Simon Müller Silke Schreiner Peter Friedhoff Stefan Hüttelmaier Dierk Niessing Michael Sattler Andreas Schlundt Albrecht Bindereif Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
description |
Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protein IMP3. |
format |
article |
author |
Tim Schneider Lee-Hsueh Hung Masood Aziz Anna Wilmen Stephanie Thaum Jacqueline Wagner Robert Janowski Simon Müller Silke Schreiner Peter Friedhoff Stefan Hüttelmaier Dierk Niessing Michael Sattler Andreas Schlundt Albrecht Bindereif |
author_facet |
Tim Schneider Lee-Hsueh Hung Masood Aziz Anna Wilmen Stephanie Thaum Jacqueline Wagner Robert Janowski Simon Müller Silke Schreiner Peter Friedhoff Stefan Hüttelmaier Dierk Niessing Michael Sattler Andreas Schlundt Albrecht Bindereif |
author_sort |
Tim Schneider |
title |
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
title_short |
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
title_full |
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
title_fullStr |
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
title_full_unstemmed |
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 |
title_sort |
combinatorial recognition of clustered rna elements by the multidomain rna-binding protein imp3 |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/cc6cce93f90546a49171482eb793687f |
work_keys_str_mv |
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