Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

Multidomain RNA-binding proteins recognize specific target sequences through mechanisms that are not well understood. Here the authors present an integrated approach to define the RNA-binding specificity and RNP topology and apply it to the analysis of the prototypical multidomain RNA-binding protei...

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Autores principales: Tim Schneider, Lee-Hsueh Hung, Masood Aziz, Anna Wilmen, Stephanie Thaum, Jacqueline Wagner, Robert Janowski, Simon Müller, Silke Schreiner, Peter Friedhoff, Stefan Hüttelmaier, Dierk Niessing, Michael Sattler, Andreas Schlundt, Albrecht Bindereif
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/cc6cce93f90546a49171482eb793687f
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