Contextual dependencies expand the re-usability of genetic inverters

Genetic circuits can be engineered to generate predefined outcomes, however host context is a crucial factor in performance. Here the authors characterise twenty NOT gates in seven different bacteria to understand and predict interoperability and portability across hosts.

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Autores principales:	Huseyin Tas, Lewis Grozinger, Ruud Stoof, Victor de Lorenzo, Ángel Goñi-Moreno
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cc80afe3b1d048be9b7194d29717c1e4
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spelling	oai:doaj.org-article:cc80afe3b1d048be9b7194d29717c1e42021-12-02T14:01:26ZContextual dependencies expand the re-usability of genetic inverters10.1038/s41467-020-20656-52041-1723https://doaj.org/article/cc80afe3b1d048be9b7194d29717c1e42021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20656-5https://doaj.org/toc/2041-1723Genetic circuits can be engineered to generate predefined outcomes, however host context is a crucial factor in performance. Here the authors characterise twenty NOT gates in seven different bacteria to understand and predict interoperability and portability across hosts.Huseyin TasLewis GrozingerRuud StoofVictor de LorenzoÁngel Goñi-MorenoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Huseyin Tas Lewis Grozinger Ruud Stoof Victor de Lorenzo Ángel Goñi-Moreno Contextual dependencies expand the re-usability of genetic inverters
description	Genetic circuits can be engineered to generate predefined outcomes, however host context is a crucial factor in performance. Here the authors characterise twenty NOT gates in seven different bacteria to understand and predict interoperability and portability across hosts.
format	article
author	Huseyin Tas Lewis Grozinger Ruud Stoof Victor de Lorenzo Ángel Goñi-Moreno
author_facet	Huseyin Tas Lewis Grozinger Ruud Stoof Victor de Lorenzo Ángel Goñi-Moreno
author_sort	Huseyin Tas
title	Contextual dependencies expand the re-usability of genetic inverters
title_short	Contextual dependencies expand the re-usability of genetic inverters
title_full	Contextual dependencies expand the re-usability of genetic inverters
title_fullStr	Contextual dependencies expand the re-usability of genetic inverters
title_full_unstemmed	Contextual dependencies expand the re-usability of genetic inverters
title_sort	contextual dependencies expand the re-usability of genetic inverters
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cc80afe3b1d048be9b7194d29717c1e4
work_keys_str_mv	AT huseyintas contextualdependenciesexpandthereusabilityofgeneticinverters AT lewisgrozinger contextualdependenciesexpandthereusabilityofgeneticinverters AT ruudstoof contextualdependenciesexpandthereusabilityofgeneticinverters AT victordelorenzo contextualdependenciesexpandthereusabilityofgeneticinverters AT angelgonimoreno contextualdependenciesexpandthereusabilityofgeneticinverters
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Contextual dependencies expand the re-usability of genetic inverters

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