Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a c...
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Mattioli1885
2019
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oai:doaj.org-article:cc86210f38664bab960ec91afbd631a42021-11-17T08:29:29ZIncidental Merkel cell carcinoma in a cutaneous horn: a case report.10.5826/dpc.0501a082160-9381https://doaj.org/article/cc86210f38664bab960ec91afbd631a42019-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/855https://doaj.org/toc/2160-9381 Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn. Brian A. SchickJoshua S. TobeMariamma G. JosephTyler B. RouseManal Y. GabrilMattioli1885articleMerkel cell carcinomasquamous cell carcinomacutaneous hornDermatologyRL1-803ENDermatology Practical & Conceptual (2019) |
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DOAJ |
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EN |
topic |
Merkel cell carcinoma squamous cell carcinoma cutaneous horn Dermatology RL1-803 |
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Merkel cell carcinoma squamous cell carcinoma cutaneous horn Dermatology RL1-803 Brian A. Schick Joshua S. Tobe Mariamma G. Joseph Tyler B. Rouse Manal Y. Gabril Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
description |
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.
|
format |
article |
author |
Brian A. Schick Joshua S. Tobe Mariamma G. Joseph Tyler B. Rouse Manal Y. Gabril |
author_facet |
Brian A. Schick Joshua S. Tobe Mariamma G. Joseph Tyler B. Rouse Manal Y. Gabril |
author_sort |
Brian A. Schick |
title |
Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
title_short |
Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
title_full |
Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
title_fullStr |
Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
title_full_unstemmed |
Incidental Merkel cell carcinoma in a cutaneous horn: a case report. |
title_sort |
incidental merkel cell carcinoma in a cutaneous horn: a case report. |
publisher |
Mattioli1885 |
publishDate |
2019 |
url |
https://doaj.org/article/cc86210f38664bab960ec91afbd631a4 |
work_keys_str_mv |
AT brianaschick incidentalmerkelcellcarcinomainacutaneoushornacasereport AT joshuastobe incidentalmerkelcellcarcinomainacutaneoushornacasereport AT mariammagjoseph incidentalmerkelcellcarcinomainacutaneoushornacasereport AT tylerbrouse incidentalmerkelcellcarcinomainacutaneoushornacasereport AT manalygabril incidentalmerkelcellcarcinomainacutaneoushornacasereport |
_version_ |
1718425765627822080 |