Incidental Merkel cell carcinoma in a cutaneous horn: a case report.

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a c...

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Autores principales: Brian A. Schick, Joshua S. Tobe, Mariamma G. Joseph, Tyler B. Rouse, Manal Y. Gabril
Formato: article
Lenguaje:EN
Publicado: Mattioli1885 2019
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Acceso en línea:https://doaj.org/article/cc86210f38664bab960ec91afbd631a4
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spelling oai:doaj.org-article:cc86210f38664bab960ec91afbd631a42021-11-17T08:29:29ZIncidental Merkel cell carcinoma in a cutaneous horn: a case report.10.5826/dpc.0501a082160-9381https://doaj.org/article/cc86210f38664bab960ec91afbd631a42019-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/855https://doaj.org/toc/2160-9381 Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn. Brian A. SchickJoshua S. TobeMariamma G. JosephTyler B. RouseManal Y. GabrilMattioli1885articleMerkel cell carcinomasquamous cell carcinomacutaneous hornDermatologyRL1-803ENDermatology Practical & Conceptual (2019)
institution DOAJ
collection DOAJ
language EN
topic Merkel cell carcinoma
squamous cell carcinoma
cutaneous horn
Dermatology
RL1-803
spellingShingle Merkel cell carcinoma
squamous cell carcinoma
cutaneous horn
Dermatology
RL1-803
Brian A. Schick
Joshua S. Tobe
Mariamma G. Joseph
Tyler B. Rouse
Manal Y. Gabril
Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
description Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a “cutaneous horn” on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.
format article
author Brian A. Schick
Joshua S. Tobe
Mariamma G. Joseph
Tyler B. Rouse
Manal Y. Gabril
author_facet Brian A. Schick
Joshua S. Tobe
Mariamma G. Joseph
Tyler B. Rouse
Manal Y. Gabril
author_sort Brian A. Schick
title Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
title_short Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
title_full Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
title_fullStr Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
title_full_unstemmed Incidental Merkel cell carcinoma in a cutaneous horn: a case report.
title_sort incidental merkel cell carcinoma in a cutaneous horn: a case report.
publisher Mattioli1885
publishDate 2019
url https://doaj.org/article/cc86210f38664bab960ec91afbd631a4
work_keys_str_mv AT brianaschick incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT joshuastobe incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT mariammagjoseph incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT tylerbrouse incidentalmerkelcellcarcinomainacutaneoushornacasereport
AT manalygabril incidentalmerkelcellcarcinomainacutaneoushornacasereport
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