Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

Pär Johansson,1 Ryo Jimbo,1 Per Kjellin,2 Fredrik Currie,2 Bruno Ramos Chrcanovic,1 Ann Wennerberg1 1Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; 2Promimic AB, Göteborg, Sweden Abstract: Polyether ether ketone (PEEK) is...

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Autores principales:	Johansson P, Jimbo R, Kjellin P, Currie F, Chrcanovic BR, Wennerberg A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/cc872d8f243b42b4aa5de4c80b465563
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spelling	oai:doaj.org-article:cc872d8f243b42b4aa5de4c80b4655632021-12-02T02:21:12ZBiomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia1178-2013https://doaj.org/article/cc872d8f243b42b4aa5de4c80b4655632014-08-01T00:00:00Zhttp://www.dovepress.com/biomechanical-evaluation-and-surface-characterization-of-a-nano-modifi-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Pär Johansson,1 Ryo Jimbo,1 Per Kjellin,2 Fredrik Currie,2 Bruno Ramos Chrcanovic,1 Ann Wennerberg1 1Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; 2Promimic AB, Göteborg, Sweden Abstract: Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (P=0.05) and 12 weeks (P=0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility. Keywords: polyether ether ketone, hydroxyapatite, removal torque, nanotopographyJohansson PJimbo RKjellin PCurrie FChrcanovic BRWennerberg ADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 3903-3911 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Johansson P Jimbo R Kjellin P Currie F Chrcanovic BR Wennerberg A Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
description	Pär Johansson,1 Ryo Jimbo,1 Per Kjellin,2 Fredrik Currie,2 Bruno Ramos Chrcanovic,1 Ann Wennerberg1 1Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; 2Promimic AB, Göteborg, Sweden Abstract: Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (P=0.05) and 12 weeks (P=0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility. Keywords: polyether ether ketone, hydroxyapatite, removal torque, nanotopography
format	article
author	Johansson P Jimbo R Kjellin P Currie F Chrcanovic BR Wennerberg A
author_facet	Johansson P Jimbo R Kjellin P Currie F Chrcanovic BR Wennerberg A
author_sort	Johansson P
title	Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
title_short	Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
title_full	Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
title_fullStr	Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
title_full_unstemmed	Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia
title_sort	biomechanical evaluation and surface characterization of a nano-modified surface on peek implants: a study in the rabbit tibia
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/cc872d8f243b42b4aa5de4c80b465563
work_keys_str_mv	AT johanssonp biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia AT jimbor biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia AT kjellinp biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia AT currief biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia AT chrcanovicbr biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia AT wennerberga biomechanicalevaluationandsurfacecharacterizationofananomodifiedsurfaceonpeekimplantsastudyintherabbittibia
_version_	1718402556102705152

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: a study in the rabbit tibia

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