The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations.
The Formyl Peptide Receptor 1 (FPR1) is an important chemotaxis receptor involved in various aspects of host defense and inflammatory processes. We constructed a model of FPR1 using as a novel template the chemokine receptor CXCR4 from the same branch of the phylogenetic tree of G-protein-coupled re...
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Autores principales: | Shuguang Yuan, Umesh Ghoshdastider, Bartosz Trzaskowski, Dorota Latek, Aleksander Debinski, Wojciech Pulawski, Rongliang Wu, Volker Gerke, Slawomir Filipek |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/cc8f9f9a470741c299a4184e46b8e740 |
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