The role of water in activation mechanism of human N-formyl peptide receptor 1 (FPR1) based on molecular dynamics simulations.

The Formyl Peptide Receptor 1 (FPR1) is an important chemotaxis receptor involved in various aspects of host defense and inflammatory processes. We constructed a model of FPR1 using as a novel template the chemokine receptor CXCR4 from the same branch of the phylogenetic tree of G-protein-coupled re...

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Autores principales: Shuguang Yuan, Umesh Ghoshdastider, Bartosz Trzaskowski, Dorota Latek, Aleksander Debinski, Wojciech Pulawski, Rongliang Wu, Volker Gerke, Slawomir Filipek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/cc8f9f9a470741c299a4184e46b8e740
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