THREE CASES WITH BURKITT LYMPHOMA PRESENTING WITH CHOLESTASIS

Case report: Cholestasis secondary to neoplasm is rare in children. It is also rare in Burkitt lymphoma and may be cause to treatment delay. We report 3 cases diagnosed with Burkitt lymphoma with cholestasis. All patients had jaundice and high direct biluribin levels. They were given LMB chemotherap...

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Main Authors: Fatma Tuba YILDIRIM, Derya ÖZYÖRÜK, Arzu YAZAL ERDEM, Selma ÇAKMAKCI, Neriman SARI, Sonay İNCESOY, İnci İLHAN
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/cc96e4bf3ec84dbd9b23b549c83383d8
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Summary:Case report: Cholestasis secondary to neoplasm is rare in children. It is also rare in Burkitt lymphoma and may be cause to treatment delay. We report 3 cases diagnosed with Burkitt lymphoma with cholestasis. All patients had jaundice and high direct biluribin levels. They were given LMB chemotherapy protocol. After COP chemotherapy, cholestasis disapperead rapidly in all patients. In conclusion, cholestasis at initial resolves rapidly with chemotherapy despite high liver function tests in Burkitt lymphoma.