BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants

BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants

In plants, 3′ Pol II pausing helps prevent transcriptional interference. Here the authors provide evidence that BORDER proteins are enriched in intergenic regions and inhibit transcriptional interference between closely spaced genes by preventing RNA polymerase from intruding into the promoters of n...

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Autores principales: Xuhong Yu, Pascal G. P. Martin, Scott D. Michaels
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/cca32344f99e4f9892623ebc478613c3
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spelling oai:doaj.org-article:cca32344f99e4f9892623ebc478613c32021-12-02T17:01:48ZBORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants10.1038/s41467-019-12328-w2041-1723https://doaj.org/article/cca32344f99e4f9892623ebc478613c32019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12328-whttps://doaj.org/toc/2041-1723In plants, 3′ Pol II pausing helps prevent transcriptional interference. Here the authors provide evidence that BORDER proteins are enriched in intergenic regions and inhibit transcriptional interference between closely spaced genes by preventing RNA polymerase from intruding into the promoters of nearby downstream genes.Xuhong YuPascal G. P. MartinScott D. MichaelsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xuhong Yu
Pascal G. P. Martin
Scott D. Michaels
BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
description In plants, 3′ Pol II pausing helps prevent transcriptional interference. Here the authors provide evidence that BORDER proteins are enriched in intergenic regions and inhibit transcriptional interference between closely spaced genes by preventing RNA polymerase from intruding into the promoters of nearby downstream genes.
format article
author Xuhong Yu
Pascal G. P. Martin
Scott D. Michaels
author_facet Xuhong Yu
Pascal G. P. Martin
Scott D. Michaels
author_sort Xuhong Yu
title BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
title_short BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
title_full BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
title_fullStr BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
title_full_unstemmed BORDER proteins protect expression of neighboring genes by promoting 3′ Pol II pausing in plants
title_sort border proteins protect expression of neighboring genes by promoting 3′ pol ii pausing in plants
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/cca32344f99e4f9892623ebc478613c3
work_keys_str_mv AT xuhongyu borderproteinsprotectexpressionofneighboringgenesbypromoting3poliipausinginplants
AT pascalgpmartin borderproteinsprotectexpressionofneighboringgenesbypromoting3poliipausinginplants
AT scottdmichaels borderproteinsprotectexpressionofneighboringgenesbypromoting3poliipausinginplants
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