Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2.
The High-Mobility Group AT-Hook 1 (HMGA1) protein is an architectural transcription factor that binds to AT-rich sequences in the promoter region of DNA and functions as a specific cofactor for gene activation. Previously, we demonstrated that HMGA1 is a key regulator of the insulin receptor (INSR)...
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Autores principales: | Eusebio Chiefari, Biagio Arcidiacono, Katiuscia Possidente, Stefania Iiritano, Valeria Ventura, Rosantony Pandolfo, Francesco Saverio Brunetti, Manfredi Greco, Daniela Foti, Antonio Brunetti |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/ccad7341346a4ada9f1b1c056aba5ca1 |
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