Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2.

Transcriptional regulation of the HMGA1 gene by octamer-binding proteins Oct-1 and Oct-2.

The High-Mobility Group AT-Hook 1 (HMGA1) protein is an architectural transcription factor that binds to AT-rich sequences in the promoter region of DNA and functions as a specific cofactor for gene activation. Previously, we demonstrated that HMGA1 is a key regulator of the insulin receptor (INSR)...

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Bibliographic Details
Main Authors: Eusebio Chiefari, Biagio Arcidiacono, Katiuscia Possidente, Stefania Iiritano, Valeria Ventura, Rosantony Pandolfo, Francesco Saverio Brunetti, Manfredi Greco, Daniela Foti, Antonio Brunetti
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/ccad7341346a4ada9f1b1c056aba5ca1
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