The molecular dynamics of subdistal appendages in multi-ciliated cells

Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.

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Autores principales: Hyunchul Ryu, Haeryung Lee, Jiyeon Lee, Hyuna Noh, Miram Shin, Vijay Kumar, Sejeong Hong, Jaebong Kim, Soochul Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ccafb702f261463a9959a435e6aae013
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spelling oai:doaj.org-article:ccafb702f261463a9959a435e6aae0132021-12-02T13:57:32ZThe molecular dynamics of subdistal appendages in multi-ciliated cells10.1038/s41467-021-20902-42041-1723https://doaj.org/article/ccafb702f261463a9959a435e6aae0132021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20902-4https://doaj.org/toc/2041-1723Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.Hyunchul RyuHaeryung LeeJiyeon LeeHyuna NohMiram ShinVijay KumarSejeong HongJaebong KimSoochul ParkNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hyunchul Ryu
Haeryung Lee
Jiyeon Lee
Hyuna Noh
Miram Shin
Vijay Kumar
Sejeong Hong
Jaebong Kim
Soochul Park
The molecular dynamics of subdistal appendages in multi-ciliated cells
description Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.
format article
author Hyunchul Ryu
Haeryung Lee
Jiyeon Lee
Hyuna Noh
Miram Shin
Vijay Kumar
Sejeong Hong
Jaebong Kim
Soochul Park
author_facet Hyunchul Ryu
Haeryung Lee
Jiyeon Lee
Hyuna Noh
Miram Shin
Vijay Kumar
Sejeong Hong
Jaebong Kim
Soochul Park
author_sort Hyunchul Ryu
title The molecular dynamics of subdistal appendages in multi-ciliated cells
title_short The molecular dynamics of subdistal appendages in multi-ciliated cells
title_full The molecular dynamics of subdistal appendages in multi-ciliated cells
title_fullStr The molecular dynamics of subdistal appendages in multi-ciliated cells
title_full_unstemmed The molecular dynamics of subdistal appendages in multi-ciliated cells
title_sort molecular dynamics of subdistal appendages in multi-ciliated cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ccafb702f261463a9959a435e6aae013
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