The molecular dynamics of subdistal appendages in multi-ciliated cells
Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.
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Nature Portfolio
2021
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oai:doaj.org-article:ccafb702f261463a9959a435e6aae0132021-12-02T13:57:32ZThe molecular dynamics of subdistal appendages in multi-ciliated cells10.1038/s41467-021-20902-42041-1723https://doaj.org/article/ccafb702f261463a9959a435e6aae0132021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20902-4https://doaj.org/toc/2041-1723Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.Hyunchul RyuHaeryung LeeJiyeon LeeHyuna NohMiram ShinVijay KumarSejeong HongJaebong KimSoochul ParkNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q Hyunchul Ryu Haeryung Lee Jiyeon Lee Hyuna Noh Miram Shin Vijay Kumar Sejeong Hong Jaebong Kim Soochul Park The molecular dynamics of subdistal appendages in multi-ciliated cells |
description |
Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot. |
format |
article |
author |
Hyunchul Ryu Haeryung Lee Jiyeon Lee Hyuna Noh Miram Shin Vijay Kumar Sejeong Hong Jaebong Kim Soochul Park |
author_facet |
Hyunchul Ryu Haeryung Lee Jiyeon Lee Hyuna Noh Miram Shin Vijay Kumar Sejeong Hong Jaebong Kim Soochul Park |
author_sort |
Hyunchul Ryu |
title |
The molecular dynamics of subdistal appendages in multi-ciliated cells |
title_short |
The molecular dynamics of subdistal appendages in multi-ciliated cells |
title_full |
The molecular dynamics of subdistal appendages in multi-ciliated cells |
title_fullStr |
The molecular dynamics of subdistal appendages in multi-ciliated cells |
title_full_unstemmed |
The molecular dynamics of subdistal appendages in multi-ciliated cells |
title_sort |
molecular dynamics of subdistal appendages in multi-ciliated cells |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/ccafb702f261463a9959a435e6aae013 |
work_keys_str_mv |
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