The molecular dynamics of subdistal appendages in multi-ciliated cells

Cilia originate from a basal body and basal foot, but the precise molecular mechanisms of basal foot biogenesis are unclear. Here, the authors show that ANKS1A interacts with FOP to transform the subdistal appendages from an unpolarized structure to a polarized structure with a basal foot.

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Bibliographic Details
Main Authors: Hyunchul Ryu, Haeryung Lee, Jiyeon Lee, Hyuna Noh, Miram Shin, Vijay Kumar, Sejeong Hong, Jaebong Kim, Soochul Park
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/ccafb702f261463a9959a435e6aae013
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