DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus

DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus

Group 2 innate lymphoid cells (ILC2s) are immune cells present in adipose tissue that contribute to metabolic homeostasis. Here the authors show that Death Receptor 3 (DR3) engagement on ILC2s ameliorates glucose tolerance, protects against insulin-resistance onset and reverses established insulin-r...

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Autores principales: Pedram Shafiei-Jahani, Benjamin P. Hurrell, Lauriane Galle-Treger, Doumet Georges Helou, Emily Howard, Jacob Painter, Richard Lo, Gavin Lewis, Pejman Soroosh, Omid Akbari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ccb0b1c8242f4157b1256882b0fb6cb3
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