The Two-Component System CopRS Maintains Subfemtomolar Levels of Free Copper in the Periplasm of <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Using a Phosphatase-Based Mechanism
ABSTRACT Two-component systems control periplasmic Cu+ homeostasis in Gram-negative bacteria. In characterized systems such as Escherichia coli CusRS, upon Cu+ binding to the periplasmic sensing region of CusS, a cytoplasmic phosphotransfer domain of the sensor phosphorylates the response regulator...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/ccbb9e02c5c14a1d97da7f3496cfffcb |
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