Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study

Novel coronavirus disease 2019 (COVID-19), caused by novel coronavirus SARS-CoV-2, has spread globally since the end of 2019. Asymptomatic carriers are of great concern as they can undermine the interventions to stop the pandemic. However, there is limited information about the characteristics and o...

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Autores principales:	Chao Yu, Miao Zhou, Yang Liu, Tinglin Guo, Chongyang Ou, Liye Yang, Yan Li, Dongliang Li, Xinyu Hu, Li Shuai, Bin Wang, Zui Zou
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2020
Materias:	covid-19 asymptomatic hypertension early treatment Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/ccbed92a4f664bdf83ce20a474d3088c
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spelling	oai:doaj.org-article:ccbed92a4f664bdf83ce20a474d3088c2021-11-17T14:21:58ZCharacteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study2150-55942150-560810.1080/21505594.2020.1802194https://doaj.org/article/ccbed92a4f664bdf83ce20a474d3088c2020-12-01T00:00:00Zhttp://dx.doi.org/10.1080/21505594.2020.1802194https://doaj.org/toc/2150-5594https://doaj.org/toc/2150-5608Novel coronavirus disease 2019 (COVID-19), caused by novel coronavirus SARS-CoV-2, has spread globally since the end of 2019. Asymptomatic carriers are of great concern as they can undermine the interventions to stop the pandemic. However, there is limited information about the characteristics and outcomes of the asymptomatic patients. Therefore, we conducted this retrospective study and retrieved data of 79 asymptomatic COVID-19 patients at admission from three designated hospitals in Wuhan, China. The asymptomatic patients could happen at any age, ranged from 9 to 96 years. These patients also had lower levels of alanine aminotransferase and C-reactive protein. Patchy shadowing was the most common manifestation in computed tomography scan. Some asymptomatic carriers developed mild or moderate symptoms during hospitalization. Age and comorbidities, especially hypertension, may be predictive factors for symptom development in the initially asymptomatic carriers at admission. Early detection and treatment for these presymptomatic patients before symptom onset can shorten the communicable period for the coronavirus and reduce the occurrence of severe cases.Chao YuMiao ZhouYang LiuTinglin GuoChongyang OuLiye YangYan LiDongliang LiXinyu HuLi ShuaiBin WangZui ZouTaylor & Francis Grouparticlecovid-19asymptomatichypertensionearly treatmentInfectious and parasitic diseasesRC109-216ENVirulence, Vol 11, Iss 1, Pp 1006-1014 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 asymptomatic hypertension early treatment Infectious and parasitic diseases RC109-216
spellingShingle	covid-19 asymptomatic hypertension early treatment Infectious and parasitic diseases RC109-216 Chao Yu Miao Zhou Yang Liu Tinglin Guo Chongyang Ou Liye Yang Yan Li Dongliang Li Xinyu Hu Li Shuai Bin Wang Zui Zou Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
description	Novel coronavirus disease 2019 (COVID-19), caused by novel coronavirus SARS-CoV-2, has spread globally since the end of 2019. Asymptomatic carriers are of great concern as they can undermine the interventions to stop the pandemic. However, there is limited information about the characteristics and outcomes of the asymptomatic patients. Therefore, we conducted this retrospective study and retrieved data of 79 asymptomatic COVID-19 patients at admission from three designated hospitals in Wuhan, China. The asymptomatic patients could happen at any age, ranged from 9 to 96 years. These patients also had lower levels of alanine aminotransferase and C-reactive protein. Patchy shadowing was the most common manifestation in computed tomography scan. Some asymptomatic carriers developed mild or moderate symptoms during hospitalization. Age and comorbidities, especially hypertension, may be predictive factors for symptom development in the initially asymptomatic carriers at admission. Early detection and treatment for these presymptomatic patients before symptom onset can shorten the communicable period for the coronavirus and reduce the occurrence of severe cases.
format	article
author	Chao Yu Miao Zhou Yang Liu Tinglin Guo Chongyang Ou Liye Yang Yan Li Dongliang Li Xinyu Hu Li Shuai Bin Wang Zui Zou
author_facet	Chao Yu Miao Zhou Yang Liu Tinglin Guo Chongyang Ou Liye Yang Yan Li Dongliang Li Xinyu Hu Li Shuai Bin Wang Zui Zou
author_sort	Chao Yu
title	Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
title_short	Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
title_full	Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
title_fullStr	Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
title_full_unstemmed	Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study
title_sort	characteristics of asymptomatic covid-19 infection and progression: a multicenter, retrospective study
publisher	Taylor & Francis Group
publishDate	2020
url	https://doaj.org/article/ccbed92a4f664bdf83ce20a474d3088c
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Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study

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